Kidney Nephron Determination

• Published in: Annual review of cell and developmental biology Vol. 34; p. 427
• Main Author: Oxburgh, Leif
• Format: Journal Article
• Language: English
• Published: United States 06.10.2018
• Subjects: nephrogenesis; nephron progenitor cell; nephron differentiation; mesenchyme-to-epithelium transition; organogenesis; cap mesenchyme

The nephron is a multifunctional filtration device equipped with an array of sophisticated sensors. For appropriate physiological function in the human and mouse, nephrons must be stereotypically arrayed in large numbers, and this essential structural property that defines the kidney is determined d...