Polysaccharide of Ganoderma lucidum Ameliorates Cachectic Myopathy Induced by the Combination Cisplatin plus Docetaxel in Mice

• Published in: Microbiology spectrum Vol. 11; no. 3; p. e0313022
• Main Authors: Wu, Sung-Yu, Ou, Chu-Chyn, Lee, Meng-Lin, Hsin, I-Lun, Kang, Yu-Ting, Jan, Ming-Shiou, Ko, Jiunn-Liang
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 15.06.2023
• Subjects: cachexia; chemotherapy; Ganoderma lucidum polysaccharide; Human Microbiome; microbiota; Research Article; side effect; microbiota; side effect; chemotherapy; Ganoderma lucidum polysaccharide; cachexia

Cachexia is a multifactorial syndrome driven by metabolic dysregulation, anorexia, systemic inflammation, and insulin resistance. Approximately 80% of patients with advanced cancer have cachexia, and cachexia is the cause of death in 30% of cancer patients. Cachexia is a lethal muscle-wasting syndro...