The nasal microbiota is a potential diagnostic biomarker for sepsis in critical care units

• Published in: Microbiology spectrum Vol. 12; no. 7; p. e0344123
• Main Authors: Tan, XiLan, Liu, Haiyue, Qiu, Wen, Li, Zewen, Ge, Shuang, Luo, Yuemei, Zeng, Nianyi, Chen, Manjun, Zhou, Qiqi, Cai, Shumin, Long, Jun, Cen, Zhongran, Su, Jin, Zhou, Hongwei, He, Xiaolong
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 02.07.2024
• Subjects: 16S rRNA; Acinetobacter - genetics; Acinetobacter - isolation & purification; Adult; Aged; Aged, 80 and over; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Biomarkers - analysis; Clinical Microbiology; Corynebacterium - genetics; Corynebacterium - isolation & purification; Feces - microbiology; Female; Gastrointestinal Microbiome; gut microbiota; Humans; Intensive Care Units; Machine Learning; Male; Microbiota; Middle Aged; nasal microbiota; Nose - microbiology; Pseudomonas - genetics; Pseudomonas - isolation & purification; Research Article; RNA, Ribosomal, 16S - genetics; sepsis; Sepsis - diagnosis; Sepsis - microbiology; Staphylococcus - genetics; Staphylococcus - isolation & purification; 16S rRNA; gut microbiota; sepsis; nasal microbiota

The important clinical significance of this study is that it compared the intestinal and nasal microbiota of sepsis with non-sepsis patients and determined that the nasal microbiota is more effective than the intestinal microbiota in distinguishing patients with sepsis from those without sepsis, bas...