The nasal microbiota is a potential diagnostic biomarker for sepsis in critical care units

The important clinical significance of this study is that it compared the intestinal and nasal microbiota of sepsis with non-sepsis patients and determined that the nasal microbiota is more effective than the intestinal microbiota in distinguishing patients with sepsis from those without sepsis, bas...

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Published inMicrobiology spectrum Vol. 12; no. 7; p. e0344123
Main Authors Tan, XiLan, Liu, Haiyue, Qiu, Wen, Li, Zewen, Ge, Shuang, Luo, Yuemei, Zeng, Nianyi, Chen, Manjun, Zhou, Qiqi, Cai, Shumin, Long, Jun, Cen, Zhongran, Su, Jin, Zhou, Hongwei, He, Xiaolong
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 02.07.2024
Subjects
16S rRNA
Acinetobacter - genetics
Acinetobacter - isolation & purification
Adult
Aged
Aged, 80 and over
Bacteria - classification
Bacteria - genetics
Bacteria - isolation & purification
Biomarkers - analysis
Clinical Microbiology
Corynebacterium - genetics
Corynebacterium - isolation & purification
Feces - microbiology
Female
Gastrointestinal Microbiome
gut microbiota
Humans
Intensive Care Units
Machine Learning
Male
Microbiota
Middle Aged
nasal microbiota
Nose - microbiology
Pseudomonas - genetics
Pseudomonas - isolation & purification
Research Article
RNA, Ribosomal, 16S - genetics
sepsis
Sepsis - diagnosis
Sepsis - microbiology
Staphylococcus - genetics
Staphylococcus - isolation & purification
16S rRNA
gut microbiota
sepsis
nasal microbiota
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Summary:The important clinical significance of this study is that it compared the intestinal and nasal microbiota of sepsis with non-sepsis patients and determined that the nasal microbiota is more effective than the intestinal microbiota in distinguishing patients with sepsis from those without sepsis, based on the difference in the lines of nasal specimens collected.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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The authors declare no conflict of interest.
XiLan Tan, Haiyue Liu, and Wen Qiu contributed equally to this article. The author order was determined based on their contribution to the article.
ISSN:2165-0497
2165-0497
DOI:10.1128/spectrum.03441-23