The potential association between postmenopausal hormone use and primary open-angle glaucoma

• Published in: JAMA ophthalmology Vol. 132; no. 3; p. 298
• Main Authors: Newman-Casey, Paula Anne, Talwar, Nidhi, Nan, Bin, Musch, David C, Pasquale, Louis R, Stein, Joshua D
• Format: Journal Article
• Language: English
• Published: United States 01.03.2014
• Subjects: Aged; Androgens - administration & dosage; Drug Combinations; Drug Prescriptions - statistics & numerical data; Estrogen Replacement Therapy - statistics & numerical data; Estrogens - administration & dosage; Female; Glaucoma, Open-Angle - epidemiology; Glaucoma, Open-Angle - prevention & control; Humans; Incidence; Intraocular Pressure; Managed Care Programs - statistics & numerical data; Middle Aged; Progesterone - administration & dosage; Proportional Hazards Models; Retrospective Studies; Risk Factors; Tonometry, Ocular; United States - epidemiology; United States

Retinal ganglion cells are known to express estrogen receptors and prior studies have suggested an association between postmenopausal hormone (PMH) use and decreased intraocular pressure, suggesting that PMH use may decrease the risk for primary open-angle glaucoma (POAG). To determine whether the u...