In Vitro Susceptibility to Posaconazole of 1,903 Yeast Isolates Recovered in France from 2003 to 2006 and Tested by the Method of the European Committee on Antimicrobial Susceptibility Testing

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Published inAntimicrobial Agents and Chemotherapy Vol. 51; no. 9; pp. 3378 - 3380
Main Authors Lortholary, Olivier, Dannaoui, Eric, Raoux, Dorothée, Hoinard, Damien, Datry, Annick, Paugam, André, Poirot, Jean-Louis, Lacroix, Claire, Dromer, Françoise
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.09.2007
Subjects
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - pharmacology
Biological and medical sciences
Fluconazole - pharmacology
France - epidemiology
Humans
Medical sciences
Microbial Sensitivity Tests
Mycoses
Mycoses - epidemiology
Mycoses - genetics
Pharmacology. Drug treatments
Pyrimidines - pharmacology
Susceptibility
Triazoles
Triazoles - pharmacology
Voriconazole
Yeasts
Yeasts - drug effects
France
Europe
Antifungal agent
Yeast
Sensitivity resistance
Drug susceptibility test
Triazole derivatives
Test method
Isolate
Antibacterial agent
Posaconazole
Online AccessGet full text
ISSN0066-4804
1098-6596
DOI10.1128/AAC.00496-07

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Abstract Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
AbstractList The posaconazole MIC 90 for 1,903 yeast isolates from France was 1 μg/ml (range, ≤0.015 to 8 μg/ml). Ninety percent of isolates with fluconazole MICs of ≥8 μg/ml ( n = 509) and 90% of those with voriconazole MICs of ≥2 μg/ml ( n = 80) were inhibited by 2 and 8 μg/ml of posaconazole, respectively.
The posaconazole MIC sub(90) for 1,903 yeast isolates from France was 1 mu g/ml (range, less than or equal to 0.015 to 8 mu g/ml). Ninety percent of isolates with fluconazole MICs of greater than or equal to 8 mu g/ml (n = 509) and 90% of those with voriconazole MICs of greater than or equal to 2 mu g/ml (n = 80) were inhibited by 2 and 8 mu g/ml of posaconazole, respectively.
The posaconazole MIC(90) for 1,903 yeast isolates from France was 1 microg/ml (range, < or =0.015 to 8 microg/ml). Ninety percent of isolates with fluconazole MICs of > or =8 microg/ml (n = 509) and 90% of those with voriconazole MICs of > or =2 microg/ml (n = 80) were inhibited by 2 and 8 microg/ml of posaconazole, respectively.
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
The posaconazole MIC90 for 1,903 yeast isolates from France was 1 μg/ml (range, ≤0.015 to 8 μg/ml). Ninety percent of isolates with fluconazole MICs of ≥8 μg/ml (n = 509) and 90% of those with voriconazole MICs of ≥2 μg/ml (n = 80) were inhibited by 2 and 8 μg/ml of posaconazole, respectively.
The posaconazole MIC(90) for 1,903 yeast isolates from France was 1 microg/ml (range, < or =0.015 to 8 microg/ml). Ninety percent of isolates with fluconazole MICs of > or =8 microg/ml (n = 509) and 90% of those with voriconazole MICs of > or =2 microg/ml (n = 80) were inhibited by 2 and 8 microg/ml of posaconazole, respectively.The posaconazole MIC(90) for 1,903 yeast isolates from France was 1 microg/ml (range, < or =0.015 to 8 microg/ml). Ninety percent of isolates with fluconazole MICs of > or =8 microg/ml (n = 509) and 90% of those with voriconazole MICs of > or =2 microg/ml (n = 80) were inhibited by 2 and 8 microg/ml of posaconazole, respectively.
Author the YEASTS Group
Jean-Louis Poirot
Eric Dannaoui
Olivier Lortholary
André Paugam
Damien Hoinard
Annick Datry
Françoise Dromer
Dorothée Raoux
Claire Lacroix
AuthorAffiliation Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, 1 Université René Descartes, Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, 2 Hôpital Pitié-Salpétrière, 3 Université René Descartes, Hôpital Cochin, 4 Hôpital Saint Antoine, 5 Hôpital Saint Louis, 6 Université René Descartes, Hôpital Européen Georges Pompidou, Unité de Parasitologie-Mycologie Paris, France 7
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Keywords Antifungal agent
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Sensitivity resistance
Drug susceptibility test
Triazole derivatives
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Antibacterial agent
Posaconazole
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Corresponding author. Mailing address: Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, 25 rue du Dr. Roux, 75724 Paris Cedex 15, France. Phone: 33 1 45 68 83 55. Fax: 33 1 45 68 84 20. E-mail: olortho@pasteur.fr
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Snippet Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit...
The posaconazole MIC 90 for 1,903 yeast isolates from France was 1 μg/ml (range, ≤0.015 to 8 μg/ml). Ninety percent of isolates with fluconazole MICs of ≥8...
The posaconazole MIC(90) for 1,903 yeast isolates from France was 1 microg/ml (range, < or =0.015 to 8 microg/ml). Ninety percent of isolates with fluconazole...
The posaconazole MIC90 for 1,903 yeast isolates from France was 1 μg/ml (range, ≤0.015 to 8 μg/ml). Ninety percent of isolates with fluconazole MICs of ≥8...
The posaconazole MIC sub(90) for 1,903 yeast isolates from France was 1 mu g/ml (range, less than or equal to 0.015 to 8 mu g/ml). Ninety percent of isolates...
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SubjectTerms Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - pharmacology
Biological and medical sciences
Fluconazole - pharmacology
France - epidemiology
Humans
Medical sciences
Microbial Sensitivity Tests
Mycoses
Mycoses - epidemiology
Mycoses - genetics
Pharmacology. Drug treatments
Pyrimidines - pharmacology
Susceptibility
Triazoles
Triazoles - pharmacology
Voriconazole
Yeasts
Yeasts - drug effects
Title In Vitro Susceptibility to Posaconazole of 1,903 Yeast Isolates Recovered in France from 2003 to 2006 and Tested by the Method of the European Committee on Antimicrobial Susceptibility Testing
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