Effect of Rifampin, a Potent Inducer of Drug-Metabolizing Enzymes, on the Pharmacokinetics of Raltegravir - Wenning, Larissa A.; Hanley, William D.; Brainard, Diana M.; Petry, Amelia S.; Ghosh, Kalyan; Jin, Bo; Mangin, Eric; Marbury, Thomas C.; Berg, Jolene K.; Chodakewitz, Jeffrey A.; Stone, Julie A.; Gottesdiener, Keith M.; et al. (Antimicrobial Agents and Chemotherapy, 2009)
Keywords: Adolescent; Adult; Antibiotics, Antitubercular; Antibiotics, Antitubercular - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Drug Administration Schedule; Drug Interactions; Female; HIV Integrase Inhibitors; HIV Integrase Inhibitors - pharmacokinetics; Human immunodeficiency virus 1; Humans; Male; Medical sciences; Middle Aged; Pharmacology; Pharmacology. Drug treatments; Pyrrolidinones; Pyrrolidinones - pharmacokinetics; Raltegravir Potassium; Rifampin; Rifampin - pharmacology; Young Adult; Antibiotic; Antiretroviral agent; Integrase inhibitor; Rifampicin; Enzyme; Antiviral; Drug-metabolizing enzyme; Antituberculous agent; Protein synthesis inhibitor; Antibacterial agent; Pharmacokinetics; Raltegravir