Adsorption of Bovine Serum Albumin on Poly(vinylidene fluoride) Surfaces in the Presence of Ions: A Molecular Dynamics Simulation

• Published in: The Journal of Physical Chemistry B Vol. 122; no. 6; pp. 1919 - 1928
• Main Authors: Shaikh, Abdul Rajjak, Karkhanechi, Hamed, Yoshioka, Tomohisa, Matsuyama, Hideto, Takaba, Hiromitsu, Wang, Da-Ming
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 15.02.2018; American Chemical Society (ACS)
• Subjects: adsorption; amino acids; artificial membranes; bovine serum albumin; denaturation; energy; fluorides; fouling; ions; molecular dynamics; simulation models; sodium chloride

Adsorption of bovine serum albumin (BSA) on poly­(vinylidene fluoride) (PVDF) surfaces in an aqueous environment was investigated in the presence and absence of excess ions using molecular dynamics simulations. The adsorption process involved diffusion of protein to the surface and dehydration of su...