Long-term Association of 13-Valent Pneumococcal Conjugate Vaccine Implementation With Rates of Community-Acquired Pneumonia in Children

• Published in: JAMA pediatrics Vol. 173; no. 4; p. 362
• Main Authors: Ouldali, Naïm, Levy, Corinne, Minodier, Philippe, Morin, Laurence, Biscardi, Sandra, Aurel, Marie, Dubos, François, Dommergues, Marie Alliette, Mezgueldi, Ellia, Levieux, Karine, Madhi, Fouad, Hees, Laure, Craiu, Irina, Gras Le Guen, Chrystèle, Launay, Elise, Zenkhri, Ferielle, Lorrot, Mathie, Gillet, Yves, Béchet, Stéphane, Hau, Isabelle, Martinot, Alain, Varon, Emmanuelle, Angoulvant, François, Cohen, Robert
• Format: Journal Article
• Language: English
• Published: United States 01.04.2019
• Subjects: Adolescent; Child; Child, Preschool; Community-Acquired Infections - epidemiology; Community-Acquired Infections - prevention & control; Emergency Service, Hospital; Female; France; Humans; Infant; Interrupted Time Series Analysis; Male; Pneumococcal Vaccines; Pneumonia, Pneumococcal - epidemiology; Pneumonia, Pneumococcal - prevention & control; Prospective Studies; Time Factors; Vaccination; France

In several countries, 5 years after 13-valent pneumococcal conjugate vaccine (PCV13) implementation, serotype replacement has been reported for invasive pneumococcal disease, which raises concerns about the long-term outcome of PCV13 implementation. The long-term effect of vaccination on community-a...