Biomimetic Mineralization of Three-Dimensional Printed Alginate/TEMPO-Oxidized Cellulose Nanofibril Scaffolds for Bone Tissue Engineering

• Published in: Biomacromolecules Vol. 19; no. 11; pp. 4442 - 4452
• Main Authors: Abouzeid, Ragab E, Khiari, Ramzi, Beneventi, Davide, Dufresne, Alain
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 12.11.2018
• Subjects: alginates; biomimetics; blood plasma; bones; calcium; cellulose; cellulose nanofibers; Chemical Sciences; compression strength; crosslinking; humans; hydrogels; hydroxyapatite; ions; Life Sciences; Material chemistry; mineralization; pastes; tissue engineering; viscosity; Viscosity; Hydrogels; Bone tissue engineering; Scaffolds; Biopolymers; 3D printing; Cellulose nanofibril

The three-dimensional (3D) printed scaffolds were prepared by partial cross-linking of TEMPO-oxidized cellulose nanofibril/alginate hydrogel using calcium ions for printing the hydrogel while maintaining its shape, fidelity, and preventing the collapse of the filaments. The prepared scaffolds were f...