Screening of α‑Glucosidase Inhibitors in Cichorium glandulosum Boiss. et Huet Extracts and Study of Interaction Mechanisms

• Published in: ACS omega Vol. 9; no. 17; pp. 19401 - 19417
• Main Authors: Abudurexiti, Adalaiti, Abdurahman, Abliz, Zhang, Rui, Zhong, Yewei, Lei, Yi, Qi, Shuwen, Hou, Wenhui, Ma, Xiaoli
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 30.04.2024

Cichorium glandulosum Boiss. et Huet (CGB) extract has an α-glucosidase inhibitory effect (IC50 = 59.34 ± 0.07 μg/mL, positive control drug acarbose IC50 = 126.1 ± 0.02 μg/mL), but the precise enzyme inhibitors implicated in this process are not known. The screening of α-glucosidase inhibitors in CG...