Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase

• Published in: mSphere Vol. 6; no. 1
• Main Authors: Kirkpatrick Roubidoux, Ericka, McMahon, Meagan, Carreño, Juan Manuel, Capuano, Christina, Jiang, Kaijun, Simon, Viviana, van Bakel, Harm, Wilson, Patrick, Krammer, Florian
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 10.02.2021
• Subjects: Research Article; influenza; epitopes; N2; neuraminidase; mAb

The influenza virus neuraminidase is an emerging target for universal influenza virus vaccines. However, in contrast to influenza virus hemagglutinin, we know little about antibody epitopes and antigenic sites on the neuraminidase. Characterizing and defining these sites is aiding vaccine developmen...