Physicochemical Properties, In Vitro Degradation, and Biocompatibility of Calcium Phosphate Cement Incorporating Poly(lactic-co-glycolic acid) Particles with Different Morphologies: A Comparative Study

• Published in: ACS omega Vol. 6; no. 12; pp. 8322 - 8331
• Main Authors: Lu, Teliang, He, Fupo, Ye, Jiandong
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 30.03.2021

Calcium phosphate cement (CPC) is one of the most promising synthetic biomaterials for bone defect repair, but its low degradation rate and the lack of macropores restrict its repair effect. Poly­(lactic-co-glycolic acid) (PLGA) is commonly used as an in situ pore forming agent in CPC, and the morph...