Trifluoromethylpyridine 1,3,4-Oxadiazole Derivatives: Emerging Scaffolds as Bacterial Agents

• Published in: ACS omega Vol. 6; no. 46; pp. 31093 - 31098
• Main Authors: Yu, Gang, Chen, Shunhong, Guo, Shengxin, Xu, Bixue, Wu, Jian
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 23.11.2021

A new class of trifluoromethylpyridine 1,3,4-oxadiazole derivatives (6a–6v) was obtained, and their antibacterial activities were evaluated. Some of them exhibited good activity, particularly 6a, which had the highest in vitro activity against Ralstonia solanacearum (R. solanacearum) and Xanthomonas...