Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006

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Published inAntimicrobial Agents and Chemotherapy Vol. 52; no. 2; pp. 778 - 781
Main Authors Dannaoui, E., Lortholary, O., Raoux, D., Bougnoux, M. E., Galeazzi, G., Lawrence, C., Moissenet, D., Poilane, I., Hoinard, D., Dromer, F.
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.02.2008
American Society for Microbiology (ASM)
Subjects
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - pharmacology
Biological and medical sciences
Candida - classification
Candida - drug effects
Candida albicans
Candida glabrata
Candida guilliermondii
Candida krusei
Candida parapsilosis
Candida tropicalis
Drug Resistance, Fungal
Echinocandins
Echinocandins - pharmacology
France
Humans
Life Sciences
Lipopeptides
Lipoproteins
Lipoproteins - pharmacology
Medical sciences
Microbial Sensitivity Tests - standards
Mycoses - microbiology
Pharmacology. Drug treatments
Susceptibility
Yeasts
Yeasts - classification
Yeasts - drug effects
France
Europe
Yeast
Drug susceptibility test
Enzyme
Transferases
Glycosyltransferases
Enzyme inhibitor
1,3-β-Glucan synthase
Method
Micafungin
In vitro
Echinocandine derivatives
Biological activity
Antifungal agent
Sensitivity resistance
Caspofungin
Isolate
Hexosyltransferases
Antibacterial agent
Comparative study
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AbstractList The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans , Candida glabrata , and Candida tropicalis than for Candida parapsilosis , Candida guilliermondii , and Candida krusei . A clear correlation was seen between the MICs for the two drugs.
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs.
The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs.The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans, Candida glabrata, and Candida tropicalis than for Candida parapsilosis, Candida guilliermondii, and Candida krusei. A clear correlation was seen between the MICs for the two drugs.
Author I. Poilane
G. Galeazzi
O. Lortholary
D. Moissenet
F. Dromer
C. Lawrence
D. Raoux
E. Dannaoui
D. Hoinard
M. E. Bougnoux
and the YEASTS Group
AuthorAffiliation Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, 75724 Paris Cedex 15, France, 1 Université Paris Descartes, Faculté de Médecine, AP-HP, Hôpital Européen Georges Pompidou, Unité de Parasitologie—Mycologie, 75015 Paris, France, 2 Université Paris Descartes, Faculté de Médecine, AP-HP, Hôpital Necker-Enfants-Malades, Centre d'Infectiologie Necker-Pasteur, 75015 Paris, France, 3 Université Paris Descartes, Faculté de Médecine, AP-HP, Hôpital Necker- Enfants-Malades, Laboratoire de Microbiologie, 75015 Paris, France, 4 AP-HP, Hôpital Louis Mourier, Unité de Parasitologie- Mycologie, 92701 Colombes Cedex, France, 5 AP-HP, Hôpital Raymond Poincaré, Laboratoire de Microbiologie, 92380 Garches, France, 6 AP-HP, Hôpital Armand Trousseau, Laboratoire de Bacteriologie-Virologie, 75012 Paris, France, 7 AP-HP, Hôpital Jean Verdier, Laboratoire de Microbiologie, 93140 Bondy, France 8
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Issue 2
Keywords Yeast
Drug susceptibility test
Enzyme
Transferases
Glycosyltransferases
Enzyme inhibitor
1,3-β-Glucan synthase
Method
Micafungin
In vitro
Echinocandine derivatives
Biological activity
Antifungal agent
Sensitivity resistance
Caspofungin
Isolate
Hexosyltransferases
Antibacterial agent
Comparative study
Language English
License CC BY 4.0
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
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PMCID: PMC2224715
Corresponding author. Mailing address: Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, 25, rue du Dr. Roux, 75724 Paris Cedex 15, France. Phone: 33 1 40 61 32 50. Fax: 33 1 45 68 84 20. E-mail: dannaoui@pasteur.fr
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The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for...
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SubjectTerms Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal Agents
Antifungal Agents - pharmacology
Biological and medical sciences
Candida - classification
Candida - drug effects
Candida albicans
Candida glabrata
Candida guilliermondii
Candida krusei
Candida parapsilosis
Candida tropicalis
Drug Resistance, Fungal
Echinocandins
Echinocandins - pharmacology
France
Humans
Life Sciences
Lipopeptides
Lipoproteins
Lipoproteins - pharmacology
Medical sciences
Microbial Sensitivity Tests - standards
Mycoses - microbiology
Pharmacology. Drug treatments
Susceptibility
Yeasts
Yeasts - classification
Yeasts - drug effects
Title Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006
URI http://aac.asm.org/content/52/2/778.abstract
https://www.ncbi.nlm.nih.gov/pubmed/18070978
https://journals.asm.org/doi/10.1128/AAC.01140-07
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