Reduced Structural Connectivity in Frontostriatal White Matter Tracts in the Associative Loop in Schizophrenia
Objective:The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy cont...
Saved in:
| Published in | The American journal of psychiatry Vol. 174; no. 11; pp. 1102 - 1111 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Psychiatric Association
01.11.2017
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Objective:The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects.Method:Structural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B.Results:Results showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients.Conclusions:These findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a “normal” brain-behavior correlation in chronic schizophrenia. |
|---|---|
| AbstractList | The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects.OBJECTIVEThe striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects.Structural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B.METHODStructural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B.Results showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients.RESULTSResults showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients.These findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a "normal" brain-behavior correlation in chronic schizophrenia.CONCLUSIONSThese findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a "normal" brain-behavior correlation in chronic schizophrenia. The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects. Structural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B. Results showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients. These findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a "normal" brain-behavior correlation in chronic schizophrenia. Objective:The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects.Method:Structural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B.Results:Results showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients.Conclusions:These findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a “normal” brain-behavior correlation in chronic schizophrenia. |
| Author | Lin, Pan Shenton, Martha E McCarley, Robert W Rathi, Yogesh Levitt, James J Levin, Laura Pelavin, Paula Nestor, Paul G Kubicki, Marek |
| Author_xml | – sequence: 1 givenname: James J surname: Levitt fullname: Levitt, James J email: james_levitt@hms.harvard.edu – sequence: 2 givenname: Paul G surname: Nestor fullname: Nestor, Paul G email: james_levitt@hms.harvard.edu – sequence: 3 givenname: Laura surname: Levin fullname: Levin, Laura email: james_levitt@hms.harvard.edu – sequence: 4 givenname: Paula surname: Pelavin fullname: Pelavin, Paula email: james_levitt@hms.harvard.edu – sequence: 5 givenname: Pan surname: Lin fullname: Lin, Pan email: james_levitt@hms.harvard.edu – sequence: 6 givenname: Marek surname: Kubicki fullname: Kubicki, Marek email: james_levitt@hms.harvard.edu – sequence: 7 givenname: Robert W surname: McCarley fullname: McCarley, Robert W email: james_levitt@hms.harvard.edu – sequence: 8 givenname: Martha E surname: Shenton fullname: Shenton, Martha E email: james_levitt@hms.harvard.edu – sequence: 9 givenname: Yogesh surname: Rathi fullname: Rathi, Yogesh email: james_levitt@hms.harvard.edu |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28945119$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkUtLLDEQhYMoOj7-gjS4cdNjkn4kATcyXB8wIvhAdyGTrmEy9CRtkha8v9604yC40FWRqu9UinP20bZ1FhA6JnhMCKvPVNeZsVp2Y4oJG5MaC4LLeguNSFVUOaOUb6MRxpjmoipe9tB-CMv0xAWju2iPclFWhIgRsvfQ9Bqa7CH6XsfeqzabOGtBR_Nm4ntmbHbpnY0uRG9UTOPnhYmQ3aoYwWePXukYBiouILsIwelEmTfIps51Q_9BL8x_1y08WKMO0c5ctQGOvuoBerr89zi5zqd3VzeTi2muSsFirjmtCkp1XQvFoW5mquRNxUrMuAAOdN6QpizInAlcCs0VEKyLGaEVrpgARosDdLre23n32kOIcmWChrZVFlwfJBElZZgSihN68gNdut7bdF2iOE5WsnpYePxF9bMVNLLzZqX8u9w4mYDzNaC9C8HDXGoTkxPJOq9MKwmWQ3ByCE6m4OQQnNwEl-T1D_nmhz-FxVr4Of8-_XfVBwCLr3g |
| CitedBy_id | crossref_primary_10_1016_j_jpsychires_2021_07_042 crossref_primary_10_1016_j_jpsychires_2024_09_012 crossref_primary_10_1016_j_jpsychires_2022_08_027 crossref_primary_10_1007_s10548_022_00906_z crossref_primary_10_1016_j_euroneuro_2021_04_007 crossref_primary_10_1016_j_media_2025_103509 crossref_primary_10_1016_j_tins_2018_12_004 crossref_primary_10_1016_j_schres_2018_12_011 crossref_primary_10_1016_j_schres_2020_09_008 crossref_primary_10_1007_s10548_023_00954_z crossref_primary_10_1017_neu_2023_44 crossref_primary_10_1515_mr_2022_0009 crossref_primary_10_1017_S0033291720004808 crossref_primary_10_1093_schbul_sbz129 crossref_primary_10_1007_s11682_019_00129_0 crossref_primary_10_1016_j_tins_2020_03_014 crossref_primary_10_1038_s41398_024_02832_z crossref_primary_10_1097_j_pain_0000000000001312 crossref_primary_10_1016_j_dcn_2022_101166 crossref_primary_10_1038_s41398_020_01049_0 crossref_primary_10_1016_j_bpsc_2020_04_004 crossref_primary_10_1002_mds_28257 crossref_primary_10_1038_s41398_024_03067_8 crossref_primary_10_1093_schbul_sbz062 crossref_primary_10_1038_s41380_023_02031_0 crossref_primary_10_1016_j_pscychresns_2018_08_008 crossref_primary_10_1002_hbm_25862 crossref_primary_10_1093_biolre_ioab138 crossref_primary_10_3390_ijms241411835 crossref_primary_10_1176_appi_ajp_2018_17121402 crossref_primary_10_1007_s00530_020_00649_6 crossref_primary_10_1038_s41398_020_01131_7 crossref_primary_10_1002_brb3_2535 crossref_primary_10_1007_s12264_019_00416_2 crossref_primary_10_3389_fams_2020_562929 crossref_primary_10_1016_j_bpsc_2023_05_010 crossref_primary_10_1016_j_schres_2018_08_021 crossref_primary_10_30773_pi_2022_0033 crossref_primary_10_1093_schizbullopen_sgaa057 crossref_primary_10_1016_j_ajp_2022_103269 crossref_primary_10_1016_j_brainresbull_2023_110818 crossref_primary_10_3389_fnana_2020_581685 crossref_primary_10_1093_cercor_bhab159 crossref_primary_10_1017_S0033291718003471 crossref_primary_10_30773_pi_2023_0069 crossref_primary_10_1002_hbm_23879 crossref_primary_10_3390_atmos11101098 crossref_primary_10_1016_j_biopsych_2024_07_016 |
| ContentType | Journal Article |
| Copyright | Copyright © 2017 by the American Psychiatric Association 2017 Copyright American Psychiatric Association Nov 1, 2017 |
| Copyright_xml | – notice: Copyright © 2017 by the American Psychiatric Association 2017 – notice: Copyright American Psychiatric Association Nov 1, 2017 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM K9. NAPCQ 7X8 |
| DOI | 10.1176/appi.ajp.2017.16091046 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Health & Medical Complete (Alumni) ProQuest Nursing and Allied Health Premium MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE ProQuest Health & Medical Complete (Alumni) |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1535-7228 |
| EndPage | 1111 |
| ExternalDocumentID | 28945119 10_1176_appi_ajp_2017_16091046 10.1176/appi.ajp.2017.16091046 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NIMH NIH HHS grantid: R01 MH097979 – fundername: NIMH NIH HHS grantid: R01 MH040799 – fundername: NIMH NIH HHS grantid: R01 MH102377 – fundername: NIA NIH HHS grantid: R01 AG042512 |
| GroupedDBID | - 1AW 1HT 1QT 23M 2J7 2WC 53G 55 5GY 5RE 85S 8R4 8R5 AAIKC AAPBV AAWTL ABFLS ABIVO ABPPZ ABPTK ABUFD ABZEH ACGOD ACHQT ACNCT ACVYA ADACO ADBBV ADBIT ADCOW AENEX AGNAY AHMBA ALMA_UNASSIGNED_HOLDINGS ASUFR BAJDF BAWUL CS3 DIK DZ E3Z EBS EJD EX3 F5P FH7 FJW G0H GX1 H13 HZ L7B MVM N9A NHB P2P PQEST PQQKQ Q2X RAY RXW RYA S10 SJN TAE TWZ UHB UKR ULE UPT WH7 WOQ WOW X X4V X6Y X7M XJT XZL YRY YZZ Z ZA5 ZHY ZY1 --- --Z -DZ -~X .55 .GJ 08P 0WA 1CY 1KJ 2QL 354 3O- 4.4 41~ 6J9 6TJ 7K8 8F7 AAAHA AAJMC AAKAS AAMNW AAQQT AAWTO AAYJJ AAYXX ABDPE ACBMB ACGFO ADGHP ADMHG ADZCM AERZD AETEA AFAZI AFFNX AFOSN AGHSJ AHJKT AI. BCR BKOMP BLC CITATION F8P FA8 GOZPB GRPMH HF~ HZ~ J5H LPU LXL LXN N4W NEJ OHT OK1 OVD P-O PEA Q.- RWL SKT TEORI TR2 UBC UQL VH1 VVN WHG XOL XSW YFH YOC YQI YQJ YSK YWH YXB YYQ ZCA ZGI ZKB ZRR ZXP ~A~ ~X8 AIZTS CGR CUY CVF ECM EIF NPM YIF YIN Z5M ADXHL K9. NAPCQ 7X8 |
| ID | FETCH-LOGICAL-a497t-c825322c669a8e6dba48d5740789e8e2fd1d431f79049c8ae10c3b1250579e723 |
| ISSN | 0002-953X 1535-7228 |
| IngestDate | Fri Jul 11 01:28:37 EDT 2025 Wed Aug 13 09:40:56 EDT 2025 Wed Feb 19 02:43:18 EST 2025 Tue Jul 01 04:09:08 EDT 2025 Thu Apr 24 23:02:39 EDT 2025 Tue Jan 05 19:02:14 EST 2021 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 11 |
| Keywords | Schizophrenia Associative Striatum Sensorimotor Striatum Diffusion Magnetic Resonance Imaging Prefrontal Cortex |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-a497t-c825322c669a8e6dba48d5740789e8e2fd1d431f79049c8ae10c3b1250579e723 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2017.16091046 |
| PMID | 28945119 |
| PQID | 1980722762 |
| PQPubID | 40661 |
| PageCount | 10 |
| ParticipantIDs | proquest_miscellaneous_1942702120 proquest_journals_1980722762 pubmed_primary_28945119 crossref_citationtrail_10_1176_appi_ajp_2017_16091046 crossref_primary_10_1176_appi_ajp_2017_16091046 appi_journals_10_1176_appi_ajp_2017_16091046 |
| ProviderPackageCode | RAY RYA X4V 1QT BAJDF G0H CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20171101 2017-11-00 2017-11-01 |
| PublicationDateYYYYMMDD | 2017-11-01 |
| PublicationDate_xml | – month: 11 year: 2017 text: 20171101 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Washington |
| PublicationTitle | The American journal of psychiatry |
| PublicationTitleAlternate | Am J Psychiatry |
| PublicationYear | 2017 |
| Publisher | American Psychiatric Association |
| Publisher_xml | – name: American Psychiatric Association |
| References | Manoach, DS 2000; 48 Lehéricy, S 2004; 55 Kherif, F 2008; 28 Corbetta, M 2002; 3 Nestor, PG 2010; 184 van Os, J 2009; 374 Kubicki, M 2013; 26 Ho, BC 2011; 68 Asselin, MC 2009; 66 Jenkinson, M 2004; 23 Kubicki, M 2007; 41 Ellison-Wright, I 2009; 108 Strick, PL 1986; 9 Destrieux, C 2004; 14 Rosow, LK 2013; 145 Bhatia, KP 1994; 117 McCarley, R 2007; 41 Zhang, H 2004; 42 Winton-Brown, TT 2013; 74 Lehman, J 2014; 34 Berger, DR 2014; 344 Kay, SR 1987; 13 Bose, SK 2011; 168 Fitzsimmons, J 2013; 26 Kegeles, LS 2010; 67 Woolrich, MW 2004; 23 Bamford, NS 2004; 42 Yeo, BT 2012; 108 Van de Moortele, PF 2004; 55 Choi, EY 2012; 108 Fischl, B 2004; 14 Mailly, P 2013; 33 Egerton, A 2013; 74 Ducros, M 2004; 55 Howes, O 2011; 16 Groenewegen, HJ 2013; 33 Draganski, B 2008; 28 Nestor, PG 2013; 145 Schmitz, Y 2004; 42 Crutcher, MD 1990; 13 van der Kouwe, A 2004; 14 Dickey, CC 2002; 159 Malcolm, JG 2010; 64 Desikan, RS 2006; 31 Levitt, JJ 2010; 184 Krienen, FM 2011; 106 Oldfield, RC 1971; 9 Rathi, Y 2010; 29 Howes, OD 2011; 168 Benson, ES 2000; 48 Shenton, ME 2013; 26 Jacobson, M 2014; 34 Klöppel, S 2008; 28 Bullmore, E 2009; 108 Redgrave, P 2010; 11 Aliane, V 2013; 33 Kikinis, Z 2010; 123 Turkheimer, F 2011; 168 Jenkinson, M 2012; 62 Calzavara, R 2009; 78 Chaddock, CA 2013; 74 Averbeck, BB 2014; 34 Andreasen, NC 2011; 68 Kubicki, M 2013; 145 Buckner, RL 2012; 108 Gollub, RL 2000; 48 Shenton, ME 2010; 29 Levitt, JJ 2012; 136 Smith, SM 2004; 23 Fallon, JH 2010; 123 Levitt, JJ 2013; 145 Kubicki, M 2014; 27 Jones, DK 2002; 15 Bernardi, G 1997; 78 Rodriguez, M 2010; 11 Chen, HH 2014; 344 Lee, SH 2013; 145 Levitt, JJ 2002; 159 Westin, CF 2007; 41 Basser, PJ 2002; 15 McCarley, RW 2002; 159 Ziebell, S 2011; 68 Graybiel, AM 2008; 31 Bose, S 2011; 16 Opler, LA 1987; 13 Turkheimer, F 2011; 16 De Murtas, M 1997; 78 Frankle, WG 2010; 67 Howes, OD 2009; 66 Alexander, GE 1990; 13 Kubicki, M 2010; 184 Choate, V 2014; 159 Yeo, BT 2011; 106 Michailovich, O 2010; 64 Montgomery, AJ 2009; 66 Alexander, GE 1986; 9 Cummings, JL 1993; 50 Malcolm, JG 2010; 29 Niznikiewicz, M 2014; 159 Tomassy, GS 2014; 344 Kapur, S 2009; 374 Calabresi, P 1997; 78 Nestor, PG 2014; 159 Marsden, CD 1994; 117 Quan, M 2013; 145 Smith, Y 2010; 11 Fiszbein, A 1987; 13 Niznikiewicz, M 2010; 123 DeLong, MR 1986; 9 Haber, SN 2009; 78 Beckmann, CF 2012; 62 Rathi, Y 2010; 64 Shulman, GL 2002; 3 Sepulcre, J 2011; 106 Abi-Dargham, A 2010; 67 Nestor, PG 2012; 136 Haber, SN 2003; 26 Behrens, TE 2012; 62 Shenton, ME 2014; 27 Ségonne, F 2006; 31 Alvarado, JL 2012; 136 Fischl, B 2006; 31 |
| References_xml | – volume: 123 start-page: 153 year: 2010 end-page: 159 article-title: Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia publication-title: Schizophr Res – volume: 159 start-page: 506 year: 2014 end-page: 508 article-title: Neuropsychology of reward learning and negative symptoms in schizophrenia publication-title: Schizophr Res – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 41 start-page: 15 year: 2007 end-page: 30 article-title: A review of diffusion tensor imaging studies in schizophrenia publication-title: J Psychiatr Res – volume: 108 start-page: 2242 year: 2012 end-page: 2263 article-title: The organization of the human striatum estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 41 start-page: 15 year: 2007 end-page: 30 article-title: A review of diffusion tensor imaging studies in schizophrenia publication-title: J Psychiatr Res – volume: 78 start-page: 69 year: 2009 end-page: 74 article-title: The cortico-basal ganglia integrative network: the role of the thalamus publication-title: Brain Res Bull – volume: 374 start-page: 635 year: 2009 end-page: 645 article-title: Schizophrenia publication-title: Lancet – volume: 28 start-page: 7143 year: 2008 end-page: 7152 article-title: Evidence for segregated and integrative connectivity patterns in the human basal ganglia publication-title: J Neurosci – volume: 16 start-page: 885 year: 2011 end-page: 886 article-title: Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study publication-title: Mol Psychiatry – volume: 14 start-page: 11 year: 2004 end-page: 22 article-title: Automatically parcellating the human cerebral cortex publication-title: Cereb Cortex – volume: 29 start-page: 1664 year: 2010 end-page: 1675 article-title: Filtered multitensor tractography publication-title: IEEE Trans Med Imaging – volume: 145 start-page: 11 year: 2013 end-page: 19 article-title: A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophrenia publication-title: Schizophr Res – volume: 68 start-page: 128 year: 2011 end-page: 137 article-title: Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia publication-title: Arch Gen Psychiatry – volume: 66 start-page: 13 year: 2009 end-page: 20 article-title: Elevated striatal dopamine function linked to prodromal signs of schizophrenia publication-title: Arch Gen Psychiatry – volume: 3 start-page: 201 year: 2002 end-page: 215 article-title: Control of goal-directed and stimulus-driven attention in the brain publication-title: Nature Rev – volume: 344 start-page: 319 year: 2014 end-page: 324 article-title: Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex publication-title: Science – volume: 159 start-page: 506 year: 2014 end-page: 508 article-title: Neuropsychology of reward learning and negative symptoms in schizophrenia publication-title: Schizophr Res – volume: 68 start-page: 128 year: 2011 end-page: 137 article-title: Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia publication-title: Arch Gen Psychiatry – volume: 3 start-page: 201 year: 2002 end-page: 215 article-title: Control of goal-directed and stimulus-driven attention in the brain publication-title: Nature Rev – volume: 26 start-page: 172 year: 2013 end-page: 187 article-title: Review of functional and anatomical brain connectivity findings in schizophrenia publication-title: Curr Opin Psychiatry – volume: 106 start-page: 1125 year: 2011 end-page: 1165 article-title: The organization of the human cerebral cortex estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 145 start-page: 11 year: 2013 end-page: 19 article-title: A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophrenia publication-title: Schizophr Res – volume: 23 start-page: S208 year: 2004 end-page: S219 article-title: Advances in functional and structural MR image analysis and implementation as FSL publication-title: Neuroimage – volume: 78 start-page: 39 year: 1997 end-page: 60 article-title: The neostriatum beyond the motor function: experimental and clinical evidence publication-title: Neuroscience – volume: 74 start-page: 106 year: 2013 end-page: 112 article-title: Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort publication-title: Biol Psychiatry – volume: 55 start-page: 522 year: 2004 end-page: 529 article-title: Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans publication-title: Ann Neurol – volume: 26 start-page: 172 year: 2013 end-page: 187 article-title: Review of functional and anatomical brain connectivity findings in schizophrenia publication-title: Curr Opin Psychiatry – volume: 9 start-page: 97 year: 1971 end-page: 113 article-title: The assessment and analysis of handedness: the Edinburgh Inventory publication-title: Neuropsychologia – volume: 41 start-page: 15 year: 2007 end-page: 30 article-title: A review of diffusion tensor imaging studies in schizophrenia publication-title: J Psychiatr Res – volume: 159 start-page: 1190 year: 2002 end-page: 1197 article-title: MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder publication-title: Am J Psychiatry – volume: 34 start-page: 9497 year: 2014 end-page: 9505 article-title: Estimates of projection overlap and zones of convergence within frontal-striatal circuits publication-title: J Neurosci – volume: 159 start-page: 1190 year: 2002 end-page: 1197 article-title: MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder publication-title: Am J Psychiatry – volume: 48 start-page: 99 year: 2000 end-page: 109 article-title: Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance publication-title: Biol Psychiatry – volume: 168 start-page: 1311 year: 2011 end-page: 1317 article-title: Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging study publication-title: Am J Psychiatry – volume: 42 start-page: 653 year: 2004 end-page: 663 article-title: Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals publication-title: Neuron – volume: 16 start-page: 885 year: 2011 end-page: 886 article-title: Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study publication-title: Mol Psychiatry – volume: 184 start-page: 143 year: 2010 end-page: 150 article-title: A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia publication-title: Psychiatry Res – volume: 26 start-page: 317 year: 2003 end-page: 330 article-title: The primate basal ganglia: parallel and integrative networks publication-title: J Chem Neuroanat – volume: 62 start-page: 782 year: 2012 end-page: 790 publication-title: Neuroimage – volume: 11 start-page: 760 year: 2010 end-page: 772 article-title: Goal-directed and habitual control in the basal ganglia: implications for Parkinson’s disease publication-title: Nature Rev – volume: 64 start-page: 138 year: 2010 end-page: 148 article-title: Tensor kernels for simultaneous fiber model estimation and tractography publication-title: Magn Reson Med – volume: 159 start-page: 1190 year: 2002 end-page: 1197 article-title: MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder publication-title: Am J Psychiatry – volume: 184 start-page: 143 year: 2010 end-page: 150 article-title: A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia publication-title: Psychiatry Res – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 33 start-page: 5718 year: 2013 end-page: 5727 article-title: The rat prefrontostriatal system analyzed in 3D: evidence for multiple interacting functional units publication-title: J Neurosci – volume: 64 start-page: 138 year: 2010 end-page: 148 article-title: Tensor kernels for simultaneous fiber model estimation and tractography publication-title: Magn Reson Med – volume: 374 start-page: 635 year: 2009 end-page: 645 article-title: Schizophrenia publication-title: Lancet – volume: 13 start-page: 261 year: 1987 end-page: 276 article-title: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia publication-title: Schizophr Bull – volume: 13 start-page: 261 year: 1987 end-page: 276 article-title: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia publication-title: Schizophr Bull – volume: 48 start-page: 99 year: 2000 end-page: 109 article-title: Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance publication-title: Biol Psychiatry – volume: 42 start-page: 653 year: 2004 end-page: 663 article-title: Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals publication-title: Neuron – volume: 9 start-page: 357 year: 1986 end-page: 381 article-title: Parallel organization of functionally segregated circuits linking basal ganglia and cortex publication-title: Annu Rev Neurosci – volume: 136 start-page: 55 year: 2012 end-page: 62 article-title: Fractional anisotropy and radial diffusivity: Diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophrenia publication-title: Schizophr Res – volume: 26 start-page: 172 year: 2013 end-page: 187 article-title: Review of functional and anatomical brain connectivity findings in schizophrenia publication-title: Curr Opin Psychiatry – volume: 29 start-page: 1664 year: 2010 end-page: 1675 article-title: Filtered multitensor tractography publication-title: IEEE Trans Med Imaging – volume: 11 start-page: 760 year: 2010 end-page: 772 article-title: Goal-directed and habitual control in the basal ganglia: implications for Parkinson’s disease publication-title: Nature Rev – volume: 34 start-page: 9497 year: 2014 end-page: 9505 article-title: Estimates of projection overlap and zones of convergence within frontal-striatal circuits publication-title: J Neurosci – volume: 55 start-page: 522 year: 2004 end-page: 529 article-title: Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans publication-title: Ann Neurol – volume: 78 start-page: 69 year: 2009 end-page: 74 article-title: The cortico-basal ganglia integrative network: the role of the thalamus publication-title: Brain Res Bull – volume: 145 start-page: 1 year: 2013 end-page: 10 article-title: White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia publication-title: Schizophr Res – volume: 108 start-page: 3 year: 2009 end-page: 10 article-title: Meta-analysis of diffusion tensor imaging studies in schizophrenia publication-title: Schizophr Res – volume: 55 start-page: 522 year: 2004 end-page: 529 article-title: Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans publication-title: Ann Neurol – volume: 15 start-page: 456 year: 2002 end-page: 467 article-title: Diffusion-tensor MRI: theory, experimental design and data analysis - a technical review publication-title: NMR Biomed – volume: 62 start-page: 782 year: 2012 end-page: 790 publication-title: Neuroimage – volume: 68 start-page: 128 year: 2011 end-page: 137 article-title: Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia publication-title: Arch Gen Psychiatry – volume: 168 start-page: 1311 year: 2011 end-page: 1317 article-title: Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging study publication-title: Am J Psychiatry – volume: 64 start-page: 138 year: 2010 end-page: 148 article-title: Tensor kernels for simultaneous fiber model estimation and tractography publication-title: Magn Reson Med – volume: 16 start-page: 885 year: 2011 end-page: 886 article-title: Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study publication-title: Mol Psychiatry – volume: 13 start-page: 266 year: 1990 end-page: 271 article-title: Functional architecture of basal ganglia circuits: neural substrates of parallel processing publication-title: Trends Neurosci – volume: 67 start-page: 231 year: 2010 end-page: 239 article-title: Increased synaptic dopamine function in associative regions of the striatum in schizophrenia publication-title: Arch Gen Psychiatry – volume: 67 start-page: 231 year: 2010 end-page: 239 article-title: Increased synaptic dopamine function in associative regions of the striatum in schizophrenia publication-title: Arch Gen Psychiatry – volume: 27 start-page: 179 year: 2014 end-page: 184 article-title: Diffusion tensor imaging findings and their implications in schizophrenia publication-title: Curr Opin Psychiatry – volume: 108 start-page: 2242 year: 2012 end-page: 2263 article-title: The organization of the human striatum estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 145 start-page: 1 year: 2013 end-page: 10 article-title: White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia publication-title: Schizophr Res – volume: 62 start-page: 782 year: 2012 end-page: 790 publication-title: Neuroimage – volume: 34 start-page: 9497 year: 2014 end-page: 9505 article-title: Estimates of projection overlap and zones of convergence within frontal-striatal circuits publication-title: J Neurosci – volume: 28 start-page: 7143 year: 2008 end-page: 7152 article-title: Evidence for segregated and integrative connectivity patterns in the human basal ganglia publication-title: J Neurosci – volume: 11 start-page: 760 year: 2010 end-page: 772 article-title: Goal-directed and habitual control in the basal ganglia: implications for Parkinson’s disease publication-title: Nature Rev – volume: 67 start-page: 231 year: 2010 end-page: 239 article-title: Increased synaptic dopamine function in associative regions of the striatum in schizophrenia publication-title: Arch Gen Psychiatry – volume: 78 start-page: 39 year: 1997 end-page: 60 article-title: The neostriatum beyond the motor function: experimental and clinical evidence publication-title: Neuroscience – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 106 start-page: 1125 year: 2011 end-page: 1165 article-title: The organization of the human cerebral cortex estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 117 start-page: 859 year: 1994 end-page: 876 article-title: The behavioural and motor consequences of focal lesions of the basal ganglia in man publication-title: Brain – volume: 66 start-page: 13 year: 2009 end-page: 20 article-title: Elevated striatal dopamine function linked to prodromal signs of schizophrenia publication-title: Arch Gen Psychiatry – volume: 123 start-page: 153 year: 2010 end-page: 159 article-title: Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia publication-title: Schizophr Res – volume: 123 start-page: 153 year: 2010 end-page: 159 article-title: Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia publication-title: Schizophr Res – volume: 74 start-page: 106 year: 2013 end-page: 112 article-title: Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort publication-title: Biol Psychiatry – volume: 28 start-page: 7143 year: 2008 end-page: 7152 article-title: Evidence for segregated and integrative connectivity patterns in the human basal ganglia publication-title: J Neurosci – volume: 117 start-page: 859 year: 1994 end-page: 876 article-title: The behavioural and motor consequences of focal lesions of the basal ganglia in man publication-title: Brain – volume: 78 start-page: 39 year: 1997 end-page: 60 article-title: The neostriatum beyond the motor function: experimental and clinical evidence publication-title: Neuroscience – volume: 106 start-page: 1125 year: 2011 end-page: 1165 article-title: The organization of the human cerebral cortex estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 23 start-page: S208 year: 2004 end-page: S219 article-title: Advances in functional and structural MR image analysis and implementation as FSL publication-title: Neuroimage – volume: 145 start-page: 11 year: 2013 end-page: 19 article-title: A volumetric MRI study of limbic, associative and sensorimotor striatal subregions in schizophrenia publication-title: Schizophr Res – volume: 50 start-page: 873 year: 1993 end-page: 880 article-title: Frontal-subcortical circuits and human behavior publication-title: Arch Neurol – volume: 344 start-page: 319 year: 2014 end-page: 324 article-title: Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex publication-title: Science – volume: 23 start-page: S208 year: 2004 end-page: S219 article-title: Advances in functional and structural MR image analysis and implementation as FSL publication-title: Neuroimage – volume: 145 start-page: 1 year: 2013 end-page: 10 article-title: White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia publication-title: Schizophr Res – volume: 159 start-page: 506 year: 2014 end-page: 508 article-title: Neuropsychology of reward learning and negative symptoms in schizophrenia publication-title: Schizophr Res – volume: 29 start-page: 1664 year: 2010 end-page: 1675 article-title: Filtered multitensor tractography publication-title: IEEE Trans Med Imaging – volume: 344 start-page: 319 year: 2014 end-page: 324 article-title: Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex publication-title: Science – volume: 9 start-page: 357 year: 1986 end-page: 381 article-title: Parallel organization of functionally segregated circuits linking basal ganglia and cortex publication-title: Annu Rev Neurosci – volume: 184 start-page: 143 year: 2010 end-page: 150 article-title: A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia publication-title: Psychiatry Res – volume: 48 start-page: 99 year: 2000 end-page: 109 article-title: Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance publication-title: Biol Psychiatry – volume: 31 start-page: 359 year: 2008 end-page: 387 article-title: Habits, rituals, and the evaluative brain publication-title: Annu Rev Neurosci – volume: 33 start-page: 5718 year: 2013 end-page: 5727 article-title: The rat prefrontostriatal system analyzed in 3D: evidence for multiple interacting functional units publication-title: J Neurosci – volume: 14 start-page: 11 year: 2004 end-page: 22 article-title: Automatically parcellating the human cerebral cortex publication-title: Cereb Cortex – volume: 168 start-page: 1311 year: 2011 end-page: 1317 article-title: Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging study publication-title: Am J Psychiatry – volume: 108 start-page: 2242 year: 2012 end-page: 2263 article-title: The organization of the human striatum estimated by intrinsic functional connectivity publication-title: J Neurophysiol – volume: 15 start-page: 456 year: 2002 end-page: 467 article-title: Diffusion-tensor MRI: theory, experimental design and data analysis - a technical review publication-title: NMR Biomed – volume: 9 start-page: 357 year: 1986 end-page: 381 article-title: Parallel organization of functionally segregated circuits linking basal ganglia and cortex publication-title: Annu Rev Neurosci – volume: 74 start-page: 106 year: 2013 end-page: 112 article-title: Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort publication-title: Biol Psychiatry – volume: 42 start-page: 653 year: 2004 end-page: 663 article-title: Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals publication-title: Neuron – volume: 13 start-page: 266 year: 1990 end-page: 271 article-title: Functional architecture of basal ganglia circuits: neural substrates of parallel processing publication-title: Trends Neurosci – volume: 136 start-page: 55 year: 2012 end-page: 62 article-title: Fractional anisotropy and radial diffusivity: Diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophrenia publication-title: Schizophr Res – volume: 14 start-page: 11 year: 2004 end-page: 22 article-title: Automatically parcellating the human cerebral cortex publication-title: Cereb Cortex – volume: 13 start-page: 261 year: 1987 end-page: 276 article-title: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia publication-title: Schizophr Bull – volume: 136 start-page: 55 year: 2012 end-page: 62 article-title: Fractional anisotropy and radial diffusivity: Diffusion measures of white matter abnormalities in the anterior limb of the internal capsule in schizophrenia publication-title: Schizophr Res – volume: 27 start-page: 179 year: 2014 end-page: 184 article-title: Diffusion tensor imaging findings and their implications in schizophrenia publication-title: Curr Opin Psychiatry – volume: 33 start-page: 5718 year: 2013 end-page: 5727 article-title: The rat prefrontostriatal system analyzed in 3D: evidence for multiple interacting functional units publication-title: J Neurosci – volume: 66 start-page: 13 year: 2009 end-page: 20 article-title: Elevated striatal dopamine function linked to prodromal signs of schizophrenia publication-title: Arch Gen Psychiatry – volume: 108 start-page: 3 year: 2009 end-page: 10 article-title: Meta-analysis of diffusion tensor imaging studies in schizophrenia publication-title: Schizophr Res |
| SSID | ssj0000372 |
| Score | 2.4639196 |
| Snippet | Objective:The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia... The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network.... Objective: The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal... |
| SourceID | proquest pubmed crossref appi |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1102 |
| SubjectTerms | Adult Anisotropy Brain Case-Control Studies Diffusion Magnetic Resonance Imaging Frontal Lobe - diagnostic imaging Humans Magnetic Resonance Imaging Male Middle Aged Neostriatum - diagnostic imaging Neural Pathways - diagnostic imaging NMR Nuclear magnetic resonance Prefrontal Cortex - diagnostic imaging Schizophrenia Schizophrenia - diagnostic imaging Trail Making Test White Matter - diagnostic imaging |
| Title | Reduced Structural Connectivity in Frontostriatal White Matter Tracts in the Associative Loop in Schizophrenia |
| URI | http://dx.doi.org/10.1176/appi.ajp.2017.16091046 https://www.ncbi.nlm.nih.gov/pubmed/28945119 https://www.proquest.com/docview/1980722762 https://www.proquest.com/docview/1942702120 |
| Volume | 174 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9swELdKkSZe0Ma-Ct1kJN5YRpImcfw4IRD7KA9bkXiLbMeRmJhbaYUH_gH-be4cO3GlItheosqx4yj36_nOvvsdIQesyHUqWYG7NnCJ9SQSLCsikYu8kbFWssHc4el5cXaRfbvMLweD-yBq6WYpP6u7tXkl_yNVaAO5YpbsP0i2eyg0wG-QL1xBwnB9lox_Iu-qtRiRBNYSaNjAFeVKQlwZMEyRoMAW58C0R1sP73BqSTWR2BxDOVykYyeoW334Yz5fYPuvMCQvtGNnfUKKCdknVoOn20ifW38AhQG5_THUua1p46MT-xpfOMD4lG3Rq-5r4dqxuwh3K2AFTLrdCu01LNbPdRnhXgW3lXo81pJAo4J5kq5X9cxyHC8w5e83Mo8mdquM46F1OABEtvhjAQC-JbKx8X7p6wIS_a0NspmCv2F986_f-yV9wlKXXg7THq2fFHml3WNgfcc-q7bOIw6MNWRmL8m280DolxZOr8hAmx3yYupiLF4T41BFe1TREFX0ytBVVFGLKtqiiraowl6AKhqgiiKqsH0FVW_IxenJ7PgsclU5IpFxtoxUmeawCqii4KLURS1FVtY5w_NgrkudNnVSg1XaMA7OpyqFTmI1kQma2oxr-LZvydDMjX5PaC4a0AiTOJNgJNVNJkulS9WIVMRNzTM9Ip_wM1YOxn8r67GyorKtIIAKBVB5AYxI7j93pRzDPRZauX5y3FE3btFyvDw5YuylGbwcL2MANlgXI7Lf3QZtjUdwwuj5DfbJMAE0SeMRedeioJvSg2f30Tt7ZKv_T43JEGCgP4BNvJQfLV4fAItKt6A |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Reduced+Structural+Connectivity+in+Frontostriatal+White+Matter+Tracts+in+the+Associative+Loop+in+Schizophrenia&rft.jtitle=The+American+journal+of+psychiatry&rft.au=Levitt%2C+James+J&rft.au=Nestor%2C+Paul+G&rft.au=Levin%2C+Laura&rft.au=Pelavin%2C+Paula&rft.date=2017-11-01&rft.eissn=1535-7228&rft.volume=174&rft.issue=11&rft.spage=1102&rft_id=info:doi/10.1176%2Fappi.ajp.2017.16091046&rft_id=info%3Apmid%2F28945119&rft.externalDocID=28945119 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-953X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-953X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-953X&client=summon |