Dynamics of Soft Nanomaterials Captured by Transmission Electron Microscopy in Liquid Water
In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provi...
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Published in | Journal of the American Chemical Society Vol. 136; no. 4; pp. 1162 - 1165 |
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Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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United States
American Chemical Society
29.01.2014
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Abstract | In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses. |
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AbstractList | In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses.In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses. In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ. We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses. In this paper we present in situ transmission electron microscopy (TEM) of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous state. The nanoparticles studied were obtained from the direct polymerization of a Pt(II)-containing monomer. The resulting structures provided sufficient contrast for facile imaging in situ . We contend that this technique will quickly become essential in the characterization of analogous systems, especially where dynamics are of interest in the solvated state. We describe the preparation of the synthetic micellar nanoparticles together with their characterization and motion in liquid water with comparison to conventional electron microscopy analyses. |
Author | Thompson, Matthew P Gianneschi, Nathan C Evans, James E Abellan Baeza, Patricia Patterson, Joseph P Millstone, Jill Rheingold, Arnold L Howell, Stephen B Chien, Miao-Ping Moore, Curtis E Andolina, Christopher Browning, Nigel D Proetto, Maria T Olson, Norman H Rush, Anthony M |
AuthorAffiliation | Department of Chemistry University of Pittsburgh Department of Chemistry & Biochemistry Environmental Molecular Sciences Laboratory University of California, San Diego Fundamental Computational Sciences Directorate Moores Cancer Center Pacific Northwest National Laboratory |
AuthorAffiliation_xml | – name: Department of Chemistry & Biochemistry – name: Fundamental Computational Sciences Directorate – name: University of California, San Diego – name: Department of Chemistry – name: Pacific Northwest National Laboratory – name: Moores Cancer Center – name: Environmental Molecular Sciences Laboratory – name: University of Pittsburgh – name: 1 Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA 92093 – name: 5 Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99354 – name: 4 Moores Cancer Center, University of California, San Diego, La Jolla CA 92093 – name: 3 Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 – name: 2 Fundamental Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA 99354 |
Author_xml | – sequence: 1 givenname: Maria T surname: Proetto fullname: Proetto, Maria T – sequence: 2 givenname: Anthony M surname: Rush fullname: Rush, Anthony M – sequence: 3 givenname: Miao-Ping surname: Chien fullname: Chien, Miao-Ping – sequence: 4 givenname: Patricia surname: Abellan Baeza fullname: Abellan Baeza, Patricia – sequence: 5 givenname: Joseph P surname: Patterson fullname: Patterson, Joseph P – sequence: 6 givenname: Matthew P surname: Thompson fullname: Thompson, Matthew P – sequence: 7 givenname: Norman H surname: Olson fullname: Olson, Norman H – sequence: 8 givenname: Curtis E surname: Moore fullname: Moore, Curtis E – sequence: 9 givenname: Arnold L surname: Rheingold fullname: Rheingold, Arnold L – sequence: 10 givenname: Christopher surname: Andolina fullname: Andolina, Christopher – sequence: 11 givenname: Jill surname: Millstone fullname: Millstone, Jill – sequence: 12 givenname: Stephen B surname: Howell fullname: Howell, Stephen B – sequence: 13 givenname: Nigel D surname: Browning fullname: Browning, Nigel D – sequence: 14 givenname: James E surname: Evans fullname: Evans, James E – sequence: 15 givenname: Nathan C surname: Gianneschi fullname: Gianneschi, Nathan C email: ngianneschi@ucsd.edu |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24422495$$D View this record in MEDLINE/PubMed |
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Snippet | In this paper we present in situ transmission electron microscopy of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated, aqueous... In this paper we present in situ transmission electron microscopy (TEM) of synthetic polymeric nanoparticles with emphasis on capturing motion in a solvated,... |
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SubjectTerms | image analysis Microscopy, Electron, Transmission Models, Molecular Molecular Structure nanoparticles Nanoparticles - chemistry Particle Size polymerization Polymers - chemical synthesis Polymers - chemistry Surface Properties Thermodynamics transmission electron microscopy Water - chemistry |
Title | Dynamics of Soft Nanomaterials Captured by Transmission Electron Microscopy in Liquid Water |
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