One-Pot Synthesis of Highly Dispersible Fluorescent Nanodiamonds for Bioconjugation

• Published in: Bioconjugate chemistry Vol. 29; no. 8; pp. 2786 - 2792
• Main Authors: Terada, Daiki, Sotoma, Shingo, Harada, Yoshie, Igarashi, Ryuji, Shirakawa, Masahiro
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 15.08.2018
• Subjects: Adsorption; Antibodies; Avidin; Biologists; Biomedical materials; Biomedical research; Biomolecules; Chemical compounds; Diamonds; Dispersion; Fluorescence; Fluorescent Dyes - chemistry; HeLa Cells; Humans; Integrins; Localization; Magnetic resonance; Medical imaging; Mitochondria; Nanodiamonds - chemistry; Nanoparticles; Nanostructure; Optically detected magnetic resonance; Peptides; Pharmacology; Protein adsorption; Proteins; Signal peptides

Fluorescent nanodiamonds (FNDs) have been attracting much attention as promising therapeutic agents and probes for bioimaging and nanosensing. For their biological applications, several hydrophilizing methods to enhance FND colloidal stability have been developed to suppress their aggregation and th...