PET Study Examining Pharmacokinetics, Detection and Likeability, and Dopamine Transporter Receptor Occupancy of Short- and Long-Acting Oral Methylphenidate - Spencer, Thomas J.; Biederman, Joseph; E. Ciccone, Patrick; Madras, Bertha K.; Dougherty, Darin D.; Bonab, Ali A.; Livni, Elijahu; Parasrampuria, Dolly A.; Fischman, Alan J. (The American journal of psychiatry, 2006)
Keywords: Administration, Oral; Adolescent; Adult; Attention deficit hyperactivity disorder; Behavior, Addictive - etiology; Biological and medical sciences; Brain; Brain - diagnostic imaging; Brain - drug effects; Brain - metabolism; Cocaine - analogs & derivatives; Corpus Striatum - drug effects; Corpus Striatum - metabolism; Delayed-Action Preparations; Dopamine Plasma Membrane Transport Proteins - antagonists & inhibitors; Dopamine Plasma Membrane Transport Proteins - drug effects; Dopamine Plasma Membrane Transport Proteins - metabolism; Dose-Response Relationship, Drug; Drug therapy; Female; Hospitals; Human subjects; Humans; Hyperactivity; Kinetics; Male; Medical sciences; Mental institutions; Methylphenidate - adverse effects; Methylphenidate - blood; Methylphenidate - pharmacokinetics; Middle Aged; Neuropharmacology; Osmosis; Pharmaceuticals; Pharmacology. Drug treatments; Positron-Emission Tomography; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease); Psychology. Psychoanalysis. Psychiatry; Psychopharmacology; Substance Abuse Detection; Radionuclide study; Chemotherapy; Treatment; CNS stimulant; Psychotropic; Dopamine receptor; Piperidine derivatives; Pharmacokinetics; Methylphenidate; Carrier protein; Emission tomography