Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids)

• Published in: JAMA cardiology Vol. 4; no. 9; p. 918
• Main Authors: Norrish, Gabrielle, Ding, Tao, Field, Ella, Ziólkowska, Lidia, Olivotto, Iacopo, Limongelli, Giuseppe, Anastasakis, Aristides, Weintraub, Robert, Biagini, Elena, Ragni, Luca, Prendiville, Terence, Duignan, Sophie, McLeod, Karen, Ilina, Maria, Fernández, Adrián, Bökenkamp, Regina, Baban, Anwar, Kubuš, Peter, Daubeney, Piers E F, Sarquella-Brugada, Georgia, Cesar, Sergi, Marrone, Chiara, Bhole, Vinay, Medrano, Constancio, Uzun, Orhan, Brown, Elspeth, Gran, Ferran, Castro, Francisco J, Stuart, Graham, Vignati, Gabriele, Barriales-Villa, Roberto, Guereta, Luis G, Adwani, Satish, Linter, Katie, Bharucha, Tara, Garcia-Pavia, Pablo, Rasmussen, Torsten B, Calcagnino, Margherita M, Jones, Caroline B, De Wilde, Hans, Toru-Kubo, J, Felice, Tiziana, Mogensen, Jens, Mathur, Sujeev, Reinhardt, Zdenka, O'Mahony, Constantinos, Elliott, Perry M, Omar, Rumana Z, Kaski, Juan P
• Format: Journal Article
• Language: English
• Published: United States 01.09.2019
• Subjects: Adolescent; Cardiomyopathy, Hypertrophic - complications; Cardiomyopathy, Hypertrophic - mortality; Child; Death, Sudden, Cardiac - epidemiology; Death, Sudden, Cardiac - etiology; Europe - epidemiology; Female; Follow-Up Studies; Humans; Incidence; Male; Prognosis; Retrospective Studies; Risk Assessment - methods; Risk Factors; Survival Rate - trends; Europe

Sudden cardiac death (SCD) is the most common mode of death in childhood hypertrophic cardiomyopathy (HCM), but there is no validated algorithm to identify those at highest risk. To develop and validate an SCD risk prediction model that provides individualized risk estimates. A prognostic model was...