Raman Fingerprints of SARS-CoV‑2 Omicron Subvariants: Molecular Roots of Virological Characteristics and Evolutionary Directions

• Published in: ACS infectious diseases Vol. 9; no. 11; pp. 2226 - 2251
• Main Authors: Pezzotti, Giuseppe, Ohgitani, Eriko, Fujita, Yuki, Imamura, Hayata, Pappone, Francesco, Grillo, Alfio, Nakashio, Maiko, Shin-Ya, Masaharu, Adachi, Tetsuya, Yamamoto, Toshiro, Kanamura, Narisato, Marin, Elia, Zhu, Wenliang, Inaba, Tohru, Tanino, Yoko, Nukui, Yoko, Higasa, Koichiro, Yasukochi, Yoshiki, Okuma, Kazu, Mazda, Osam
• Format: Journal Article
• Language: English
• Published: American Chemical Society 10.11.2023
• Subjects: SARS-CoV-2; Omicron subvariants; Raman spectroscopy; Raman barcode; principal component analysis

The latest RNA genomic mutation of SARS-CoV-2 virus, termed the Omicron variant, has generated a stream of highly contagious and antibody-resistant strains, which in turn led to classifying Omicron as a variant of concern. We systematically collected Raman spectra from six Omicron subvariants availa...