Unraveling the evolutionary dynamics of toxin-antitoxin systems in diverse genetic lineages of Escherichia coli including the high-risk clonal complexes

• Published in: mBio Vol. 15; no. 1; p. e0302323
• Main Authors: Singh, Anuradha, Lankapalli, Aditya Kumar, Mendem, Suresh Kumar, Semmler, Torsten, Ahmed, Niyaz
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 16.01.2024
• Subjects: adaptation; antimicrobial resistance; Antitoxins - genetics; Bacteria; Bacterial Proteins - genetics; Bacterial Toxins - genetics; Bacteriology; Escherichia coli; Escherichia coli - genetics; Escherichia coli Proteins - genetics; Humans; Research Article; sequence type (ST); toxin-antitoxin (TA) systems; Toxin-Antitoxin Systems - genetics; virulence; adaptation; toxin-antitoxin (TA) systems; virulence; antimicrobial resistance; sequence type (ST); Escherichia coli

Escherichia coli is a highly versatile microorganism with a unique ability to survive and persist in varied niches of the human and animal hosts and the environment. While commensal strains of E. coli play a crucial role in preserving and maintaining the balance and function of their community withi...