Solution Self-Assemblies of Sequence-Defined Ionic Peptoid Block Copolymers

• Published in: Journal of the American Chemical Society Vol. 140; no. 11; pp. 4100 - 4109
• Main Authors: Sternhagen, Garrett L, Gupta, Sudipta, Zhang, Yueheng, John, Vijay, Schneider, Gerald J, Zhang, Donghui
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 21.03.2018; American Chemical Society (ACS)
• Subjects: composite polymers; electrostatic interactions; hydrodynamics; hydrophilicity; hydrophobicity; ionic peptoid block copolymers; MATERIALS SCIENCE; micelles; N-substituted glycines; neutron diffraction; Sequence-defined polymers; solution self-assembly

A series of amphiphilic ionic peptoid block copolymers where the total number (1 or 3) and position of ionic monomers along the polymer chain are precisely controlled have been synthesized by the submonomer method. Upon dissolution in water at pH = 9, the amphiphilic peptoids self-assemble into smal...