Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19

• Published in: mBio Vol. 12; no. 1
• Main Authors: Pace, Ryan M., Williams, Janet E., Järvinen, Kirsi M., Belfort, Mandy B., Pace, Christina D. W., Lackey, Kimberly A., Gogel, Alexandra C., Nguyen-Contant, Phuong, Kanagaiah, Preshetha, Fitzgerald, Theresa, Ferri, Rita, Young, Bridget, Rosen-Carole, Casey, Diaz, Nichole, Meehan, Courtney L., Caffé, Beatrice, Sangster, Mark Y., Topham, David, McGuire, Mark A., Seppo, Antti, McGuire, Michelle K.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 09.02.2021
• Subjects: Adult; Antibodies, Neutralizing - metabolism; Antibodies, Viral - metabolism; Breast - virology; Breast Feeding; Clinical Science and Epidemiology; COVID-19 - immunology; COVID-19 - transmission; COVID-19 - virology; Female; Humans; Infant; Infectious Disease Transmission, Vertical; Milk, Human - immunology; Milk, Human - virology; Mothers; Pregnancy; Pregnancy Complications, Infectious - immunology; Pregnancy Complications, Infectious - virology; Research Article; RNA, Viral - isolation & purification; SARS-CoV-2 - immunology; SARS-CoV-2 - isolation & purification; COVID-19; neutralizing capacity; SARS-CoV-2; breastmilk; antibodies; human milk; breastfeeding

Results from prior studies assaying human milk for the presence of SARS-CoV-2, the causative virus of COVID-19, have suggested milk may act as a potential vehicle for mother-to-child transmission. Most previous studies are limited because they followed only a few participants, were cross-sectional,...