Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping - Sun, Bingbing; Pokhrel, Suman; Dunphy, Darren R; Zhang, Haiyuan; Ji, Zhaoxia; Wang, Xiang; Wang, Meiying; Liao, Yu-Pei; Chang, Chong Hyun; Dong, Juyao; Li, Ruibin; Mädler, Lutz; et al. (ACS nano, 2015)
Keywords: Calcium - metabolism; Cell Line; Density; Doping; Foods; Fumed silica; Humans; Liver Cirrhosis - chemically induced; Liver Cirrhosis - pathology; Lung - drug effects; Lung - pathology; Lungs; Nanoparticles - adverse effects; Nanoparticles - chemistry; Pneumonia - chemically induced; Pneumonia - pathology; Reactive Oxygen Species - toxicity; Reduction; Silanes - chemistry; Silicon Dioxide - adverse effects; Silicon Dioxide - chemistry; Siloxanes; Structure-Activity Relationship; Titanium; United States; United States Food and Drug Administration; United States; doping; fumed silica; silanol groups; NLRP3 inflammasome; IL-1β; lung inflammation