No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis
Objective:Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically e...
Saved in:
| Published in | The American journal of psychiatry Vol. 176; no. 12; pp. 1039 - 1049 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Psychiatric Association
01.12.2019
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0002-953X 1535-7228 1535-7228 |
| DOI | 10.1176/appi.ajp.2019.18101144 |
Cover
| Abstract | Objective:Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects.Methods:The authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T1-weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen’s d=0.1.Results:The largest effect size (Cohen’s d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset.Conclusions:Altered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases. |
|---|---|
| AbstractList | Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects.OBJECTIVEAsymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects.The authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T1-weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen's d=0.1.METHODSThe authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T1-weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen's d=0.1.The largest effect size (Cohen's d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset.RESULTSThe largest effect size (Cohen's d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset.Altered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases.CONCLUSIONSAltered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases. Magnetic resonance imaging (MRI) studies have shown subtle differences of brain anatomy between people with major depressive disorder (MDD) and healthy controls, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypo-activity and right parietal hypo-activity in depressive disorders, so that aspects of lateralized anatomy might also be affected. In the current study, we investigated 2256 individuals with MDD and 3504 controls, from 31 separate datasets, for differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions. We also investigated volume asymmetries of eight subcortical structures, in 2540 MDD individuals and 4230 controls, from 32 datasets. T1-weighted MRI data were processed with a single protocol using FreeSurfer software and the Desikan-Killiany atlas. The unprecedented sample size provided 80% power to detect effects of the order of Cohen’s d = 0.1. However, the largest effect size of MDD diagnosis was Cohen’s d = 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant when adjusting for multiple testing. Asymmetry measures were also not significantly associated with medication use, acute versus remitted status, first episode versus recurrent status, or age at onset. Altered brain macro-anatomical asymmetry may therefore be of little relevance to MDD aetiology in most cases. Objective: Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects. Methods: The authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T1-weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen's d=0.1. Results: The largest effect size (Cohen's d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset. Conclusions: Altered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases. Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects. The authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T -weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen's d=0.1. The largest effect size (Cohen's d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset. Altered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases. |
| Author | Connolly, Colm G Lagopoulos, Jim Rosa, Pedro G.P Stein, Dan J Davey, Christopher G Medland, Sarah E Baune, Bernhard T Frodl, Thomas Fu, Cynthia H.Y Li, Meng Schrantee, Anouk Yang, Tony T Portella, Maria J Leehr, Elisabeth J Busatto Filho, Geraldo Harrison, Ben J Sim, Kang Groenewold, Nynke A Glahn, David C Bülow, Robin Erwin-Grabner, Tracy Sindermann, Lisa Veltman, Dick J Ho, Tiffany C Van der Werff, Steven J.A Van der Wee, Nic J.A Dima, Danai Sacchet, Matthew D Vives-Gilabert, Yolanda Yüksel, Dilara Ubani, Benjamin N Thompson, Paul M Reneman, Liesbeth Winter, Nils Cullen, Kathryn R Schmaal, Lianne Gotlib, Ian H Goya-Maldonado, Roberto Mueller, Bryon A Walter, Henrik MacMaster, Frank P Whalley, Heather Alexander-Bloch, Aaron F Hatton, Sean N Veer, Ilya M Nenadic, Igor Hickie, Ian B Godlewska, Beata Aleman, André Francks, Clyde Schreiner, Melinda Westlund Osipov, Evgeny Völzke, Henry Aftanas, Lyubomir Schnell, Knut Krug, Axel Singh, Aditya Carballedo, Angela Jahanshad, Neda MacQueen, Glenda Grotegerd, Dominik Walter, Martin de Kovel, Carolien G.F M |
| AuthorAffiliation | 31 Division of Psychiatry, University of Edinburgh, Edinburgh, UK 30 Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, Canada 45 German Center for Neurodegenerative Diseases (DZNE), Site Rostock/ Greifswald, Germany 47 Department of Psychology, University of Groningen, the Netherlands 37 SA MRC Unit on Risk & Resilience, Department of Psychiatry, University of Cape Town, Cape Town, South Africa 56 Rehabilitation Services and Care Unit, Swiss Paraplegic Research, Nottwil, Switzerland 29 Psychiatry and Paediatrics, University of Calgary, Calgary, Canada 53 Sunshine Coast Mind and Neuroscience Thompson Institute, Queensland, Australia 13 Department of Psychiatry, University of Münster, Münster, Germany 58 Centre for Youth Mental Health, The University of Melbourne, Australia 49 Department of Biomedical Sciences, Florida State University, Tallahassee, USA 63 German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany 19 Department |
| AuthorAffiliation_xml | – name: 17 Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK – name: 4 Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Marina del Rey, USA – name: 49 Department of Biomedical Sciences, Florida State University, Tallahassee, USA – name: 61 Boston University School of Public Health, Boston University, Boston, USA – name: 39 Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands – name: 59 Spinoza Centre for Neuroimaging, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands – name: 35 Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, USA – name: 62 Leiden Institute for Brain and Cognition, Leiden, the Netherlands – name: 10 Department of Psychiatry, Trinity College Dublin, Ireland – name: 38 Brain function and dysfunction, Leids Universitair Medisch Centrum, Leiden, the Netherlands – name: 26 Youth Mental Health Team, Brain and Mind Centre, University of Sydney, Sydney, Australia – name: 42 Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany – name: 14 Department of Psychology, School of Arts and Social Sciences, City, University of London, London, UK – name: 6 Department of Neuroscience, NeuroImaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands – name: 16 Department of Psychiatry and Psychotherapy, Otto von Guericke University Magdeburg, Magdeburg, Germany – name: 5 Laboratory of Affective, Cognitive & Translational Neuroscience, Scientific Research Institute of Physiology & Basic Medicine, Novosibirsk, Russian Federation – name: 57 CIBERSAM, Madrid, Spain – name: 60 Yong Loo Lin School of Medicine, National University of Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore – name: 27 Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany – name: 19 Department of Psychiatry, Yale School of Medicine, New Haven, USA – name: 21 Department of Psychology, Stanford University, Stanford, USA – name: 55 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh, UK – name: 46 Department of Neuroscience, Novosibirsk State University, Novosibirsk, Russian Federation – name: 52 School of Psychology, University of East London, London, UK – name: 12 Department of Psychiatry, University of Minnesota Medical School, Minneapolis, USA – name: 30 Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, Canada – name: 1 Department Language & Genetics, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands – name: 48 Center for Interdisciplinary Research on Applied Neurosciences (NAPNA), University of São Paulo, São Paulo, Brazil – name: 3 Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands – name: 8 Institute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany – name: 18 Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, Canada – name: 13 Department of Psychiatry, University of Münster, Münster, Germany – name: 23 Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, Groningen, The Netherlands – name: 28 Department of Neurology, University of Magdeburg, Magdeburg, Germany – name: 2 Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia – name: 53 Sunshine Coast Mind and Neuroscience Thompson Institute, Queensland, Australia – name: 58 Centre for Youth Mental Health, The University of Melbourne, Australia – name: 7 Department of Psychiatry, University of Melbourne, Melbourne, Australia – name: 11 Department of Psychiatry and Weill Institutes of Neurosciences, Division of Child and Adolescent Psychiatry, University of California, San Francisco (UCSF), USA – name: 33 Department. of Psychiatry, Institute of Biomedical Research Sant Pau, Barcelona, Spain – name: 51 Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands – name: 15 Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany – name: 37 SA MRC Unit on Risk & Resilience, Department of Psychiatry, University of Cape Town, Cape Town, South Africa – name: 47 Department of Psychology, University of Groningen, the Netherlands – name: 56 Rehabilitation Services and Care Unit, Swiss Paraplegic Research, Nottwil, Switzerland – name: 63 German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany – name: 36 West Region and Research Division, Institute of Mental Health, Singapore – name: 45 German Center for Neurodegenerative Diseases (DZNE), Site Rostock/ Greifswald, Germany – name: 31 Division of Psychiatry, University of Edinburgh, Edinburgh, UK – name: 32 Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia – name: 54 Strategic Clinical Network for Addictions and Mental Health, Alberta, Canada – name: 29 Psychiatry and Paediatrics, University of Calgary, Calgary, Canada – name: 41 Instituto ITACA, Universitat Politècnica de València, València, Spain – name: 44 Department of Psychology, University of Minnesota, Minneapolis, USA – name: 43 Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen , Germany – name: 50 Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK – name: 40 Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany – name: 34 Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers , Amsterdam, the Netherlands – name: 9 Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil – name: 25 Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne & Melbourne Health, Melbourne, Australia – name: 20 Psychopharmacology Research Unit, Department of Psychiatry, University of Oxford, Oxford, UK – name: 22 Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany – name: 24 Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany |
| Author_xml | – sequence: 1 givenname: Carolien G.F surname: de Kovel fullname: de Kovel, Carolien G.F email: clyde.francks@mpi.nl – sequence: 2 givenname: Lyubomir surname: Aftanas fullname: Aftanas, Lyubomir email: clyde.francks@mpi.nl – sequence: 3 givenname: André surname: Aleman fullname: Aleman, André email: clyde.francks@mpi.nl – sequence: 4 givenname: Aaron F surname: Alexander-Bloch fullname: Alexander-Bloch, Aaron F email: clyde.francks@mpi.nl – sequence: 5 givenname: Bernhard T surname: Baune fullname: Baune, Bernhard T email: clyde.francks@mpi.nl – sequence: 6 givenname: Ivan surname: Brack fullname: Brack, Ivan email: clyde.francks@mpi.nl – sequence: 7 givenname: Robin surname: Bülow fullname: Bülow, Robin email: clyde.francks@mpi.nl – sequence: 8 givenname: Geraldo surname: Busatto Filho fullname: Busatto Filho, Geraldo email: clyde.francks@mpi.nl – sequence: 9 givenname: Angela surname: Carballedo fullname: Carballedo, Angela email: clyde.francks@mpi.nl – sequence: 10 givenname: Colm G surname: Connolly fullname: Connolly, Colm G email: clyde.francks@mpi.nl – sequence: 11 givenname: Kathryn R surname: Cullen fullname: Cullen, Kathryn R email: clyde.francks@mpi.nl – sequence: 12 givenname: Udo surname: Dannlowski fullname: Dannlowski, Udo email: clyde.francks@mpi.nl – sequence: 13 givenname: Christopher G surname: Davey fullname: Davey, Christopher G email: clyde.francks@mpi.nl – sequence: 14 givenname: Danai surname: Dima fullname: Dima, Danai email: clyde.francks@mpi.nl – sequence: 15 givenname: Katharina surname: Dohm fullname: Dohm, Katharina email: clyde.francks@mpi.nl – sequence: 16 givenname: Tracy surname: Erwin-Grabner fullname: Erwin-Grabner, Tracy email: clyde.francks@mpi.nl – sequence: 17 givenname: Thomas surname: Frodl fullname: Frodl, Thomas email: clyde.francks@mpi.nl – sequence: 18 givenname: Cynthia H.Y surname: Fu fullname: Fu, Cynthia H.Y email: clyde.francks@mpi.nl – sequence: 19 givenname: Geoffrey B surname: Hall fullname: Hall, Geoffrey B email: clyde.francks@mpi.nl – sequence: 20 givenname: David C surname: Glahn fullname: Glahn, David C email: clyde.francks@mpi.nl – sequence: 21 givenname: Beata surname: Godlewska fullname: Godlewska, Beata email: clyde.francks@mpi.nl – sequence: 22 givenname: Ian H surname: Gotlib fullname: Gotlib, Ian H email: clyde.francks@mpi.nl – sequence: 23 givenname: Roberto surname: Goya-Maldonado fullname: Goya-Maldonado, Roberto email: clyde.francks@mpi.nl – sequence: 24 givenname: Hans Jörgen surname: Grabe fullname: Grabe, Hans Jörgen email: clyde.francks@mpi.nl – sequence: 25 givenname: Nynke A surname: Groenewold fullname: Groenewold, Nynke A email: clyde.francks@mpi.nl – sequence: 26 givenname: Dominik surname: Grotegerd fullname: Grotegerd, Dominik email: clyde.francks@mpi.nl – sequence: 27 givenname: Oliver surname: Gruber fullname: Gruber, Oliver email: clyde.francks@mpi.nl – sequence: 28 givenname: Mathew A surname: Harris fullname: Harris, Mathew A email: clyde.francks@mpi.nl – sequence: 29 givenname: Ben J surname: Harrison fullname: Harrison, Ben J email: clyde.francks@mpi.nl – sequence: 30 givenname: Sean N surname: Hatton fullname: Hatton, Sean N email: clyde.francks@mpi.nl – sequence: 31 givenname: Ian B surname: Hickie fullname: Hickie, Ian B email: clyde.francks@mpi.nl – sequence: 32 givenname: Tiffany C surname: Ho fullname: Ho, Tiffany C email: clyde.francks@mpi.nl – sequence: 33 givenname: Neda surname: Jahanshad fullname: Jahanshad, Neda email: clyde.francks@mpi.nl – sequence: 34 givenname: Tilo surname: Kircher fullname: Kircher, Tilo email: clyde.francks@mpi.nl – sequence: 35 givenname: Bernd surname: Krämer fullname: Krämer, Bernd email: clyde.francks@mpi.nl – sequence: 36 givenname: Axel surname: Krug fullname: Krug, Axel email: clyde.francks@mpi.nl – sequence: 37 givenname: Jim surname: Lagopoulos fullname: Lagopoulos, Jim email: clyde.francks@mpi.nl – sequence: 38 givenname: Elisabeth J surname: Leehr fullname: Leehr, Elisabeth J email: clyde.francks@mpi.nl – sequence: 39 givenname: Meng surname: Li fullname: Li, Meng email: clyde.francks@mpi.nl – sequence: 40 givenname: Frank P surname: MacMaster fullname: MacMaster, Frank P email: clyde.francks@mpi.nl – sequence: 41 givenname: Glenda surname: MacQueen fullname: MacQueen, Glenda email: clyde.francks@mpi.nl – sequence: 42 givenname: Andrew M surname: McIntosh fullname: McIntosh, Andrew M email: clyde.francks@mpi.nl – sequence: 43 givenname: Quinn surname: McLellan fullname: McLellan, Quinn email: clyde.francks@mpi.nl – sequence: 44 givenname: Sarah E surname: Medland fullname: Medland, Sarah E email: clyde.francks@mpi.nl – sequence: 45 givenname: Bryon A surname: Mueller fullname: Mueller, Bryon A email: clyde.francks@mpi.nl – sequence: 46 givenname: Igor surname: Nenadic fullname: Nenadic, Igor email: clyde.francks@mpi.nl – sequence: 47 givenname: Evgeny surname: Osipov fullname: Osipov, Evgeny email: clyde.francks@mpi.nl – sequence: 48 givenname: Martina surname: Papmeyer fullname: Papmeyer, Martina email: clyde.francks@mpi.nl – sequence: 49 givenname: Maria J surname: Portella fullname: Portella, Maria J email: clyde.francks@mpi.nl – sequence: 50 givenname: Liesbeth surname: Reneman fullname: Reneman, Liesbeth email: clyde.francks@mpi.nl – sequence: 51 givenname: Pedro G.P surname: Rosa fullname: Rosa, Pedro G.P email: clyde.francks@mpi.nl – sequence: 52 givenname: Matthew D surname: Sacchet fullname: Sacchet, Matthew D email: clyde.francks@mpi.nl – sequence: 53 givenname: Knut surname: Schnell fullname: Schnell, Knut email: clyde.francks@mpi.nl – sequence: 54 givenname: Anouk surname: Schrantee fullname: Schrantee, Anouk email: clyde.francks@mpi.nl – sequence: 55 givenname: Kang surname: Sim fullname: Sim, Kang email: clyde.francks@mpi.nl – sequence: 56 givenname: Egle surname: Simulionyte fullname: Simulionyte, Egle email: clyde.francks@mpi.nl – sequence: 57 givenname: Lisa surname: Sindermann fullname: Sindermann, Lisa email: clyde.francks@mpi.nl – sequence: 58 givenname: Aditya surname: Singh fullname: Singh, Aditya email: clyde.francks@mpi.nl – sequence: 59 givenname: Dan J surname: Stein fullname: Stein, Dan J email: clyde.francks@mpi.nl – sequence: 60 givenname: Benjamin N surname: Ubani fullname: Ubani, Benjamin N email: clyde.francks@mpi.nl – sequence: 61 givenname: Nic J.A surname: Van der Wee fullname: Van der Wee, Nic J.A email: clyde.francks@mpi.nl – sequence: 62 givenname: Steven J.A surname: Van der Werff fullname: Van der Werff, Steven J.A email: clyde.francks@mpi.nl – sequence: 63 givenname: Ilya M surname: Veer fullname: Veer, Ilya M email: clyde.francks@mpi.nl – sequence: 64 givenname: Yolanda surname: Vives-Gilabert fullname: Vives-Gilabert, Yolanda email: clyde.francks@mpi.nl – sequence: 65 givenname: Henry surname: Völzke fullname: Völzke, Henry email: clyde.francks@mpi.nl – sequence: 66 givenname: Henrik surname: Walter fullname: Walter, Henrik email: clyde.francks@mpi.nl – sequence: 67 givenname: Martin surname: Walter fullname: Walter, Martin email: clyde.francks@mpi.nl – sequence: 68 givenname: Melinda Westlund surname: Schreiner fullname: Schreiner, Melinda Westlund email: clyde.francks@mpi.nl – sequence: 69 givenname: Heather surname: Whalley fullname: Whalley, Heather email: clyde.francks@mpi.nl – sequence: 70 givenname: Nils surname: Winter fullname: Winter, Nils email: clyde.francks@mpi.nl – sequence: 71 givenname: Katharina surname: Wittfeld fullname: Wittfeld, Katharina email: clyde.francks@mpi.nl – sequence: 72 givenname: Tony T surname: Yang fullname: Yang, Tony T email: clyde.francks@mpi.nl – sequence: 73 givenname: Dilara surname: Yüksel fullname: Yüksel, Dilara email: clyde.francks@mpi.nl – sequence: 74 givenname: Dario surname: Zaremba fullname: Zaremba, Dario email: clyde.francks@mpi.nl – sequence: 75 givenname: Paul M surname: Thompson fullname: Thompson, Paul M email: clyde.francks@mpi.nl – sequence: 76 givenname: Dick J surname: Veltman fullname: Veltman, Dick J email: clyde.francks@mpi.nl – sequence: 77 givenname: Lianne surname: Schmaal fullname: Schmaal, Lianne email: clyde.francks@mpi.nl – sequence: 78 givenname: Clyde surname: Francks fullname: Francks, Clyde email: clyde.francks@mpi.nl |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31352813$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkVFvFCEUhYmpsdvqX2hIfPFltsBlYNaYmHFb2yZtfVAT3wg7MJbNzDAC02T_vWy322hf-kTgfudwbs4ROhj8YBE6oWROqRSnehzdXK_HOSN0MacVJZRy_grNaAllIRmrDtCMEMKKRQm_DtFRjOt8JSDZG3QIFEpWUZihu1uP6y7ZoJPzQ8S-xV-CdgP-nsLUpCnoDtdx0_c2hQ3O7zd67QM-s2OwMbp7i89c9MHY8BHXAz6_vbq4qfEyW_mQ3NTnR91tootv0etWd9G-ezyP0c-v5z-Wl8X1t4urZX1daF7JVCxMZVptGkMJ1y1UpREGeEksAOVaCC6IaWXLpGwkZw1vYQF6RYGvVpVoM3uMPu98x2nVW9PYIeUd1Bhcr8NGee3U_5PB3anf_l5RRqCSjGaHD48Owf-ZbEyqd7GxXacH66eoGBMCQArGMvr-Gbr2U8gbZwoyx6UUZaZO_o30lGXfQgY-7YAm-BiDbVXj0kMhOaHrFCVqW7ralq5y6WpbutqXnuXimXz_w4tC2Akf5k_RX1D9BcGuxAc |
| CitedBy_id | crossref_primary_10_1002_hbm_25672 crossref_primary_10_1002_hbm_25033 crossref_primary_10_1016_j_nicl_2019_102056 crossref_primary_10_1016_j_jsxm_2021_03_079 crossref_primary_10_1073_pnas_2213880120 crossref_primary_10_1007_s00702_023_02610_z crossref_primary_10_1002_mhs2_13 crossref_primary_10_1016_j_biopsycho_2021_108097 crossref_primary_10_1093_psyrad_kkab015 crossref_primary_10_1016_j_biopsych_2021_11_002 crossref_primary_10_1016_j_pscychresns_2021_111378 crossref_primary_10_28982_josam_939233 crossref_primary_10_1038_s44220_023_00200_2 crossref_primary_10_1111_bdi_13139 crossref_primary_10_1038_s41582_024_00974_8 crossref_primary_10_1016_j_jad_2021_07_052 crossref_primary_10_1038_s41398_020_0842_6 crossref_primary_10_1038_s41598_024_64372_2 crossref_primary_10_3390_sym14010024 crossref_primary_10_1111_bdi_70012 crossref_primary_10_1007_s00406_024_01888_8 crossref_primary_10_1016_j_pnpbp_2021_110322 crossref_primary_10_1590_1516_4446_2019_0757 crossref_primary_10_3389_fnsys_2021_733898 crossref_primary_10_1007_s41252_019_00147_5 crossref_primary_10_1097_CM9_0000000000002538 crossref_primary_10_1111_pcn_13337 crossref_primary_10_3390_sym14122490 crossref_primary_10_1016_j_neuroimage_2021_117834 crossref_primary_10_1007_s12264_021_00638_3 crossref_primary_10_1038_s41598_023_44694_3 crossref_primary_10_1016_j_nsa_2024_104090 crossref_primary_10_1038_s44220_023_00139_4 crossref_primary_10_3389_fnbeh_2022_1054114 crossref_primary_10_1016_j_cortex_2019_12_019 crossref_primary_10_1016_j_jad_2024_09_102 crossref_primary_10_1038_s41467_024_46784_w crossref_primary_10_3758_s13415_021_00923_8 |
| Cites_doi | 10.1146/annurev-publhealth-031912-114409 10.1038/mp.2015.69 10.1016/j.bbr.2015.05.058 10.1007/s11682-016-9629-z 10.1016/j.neuroimage.2019.01.074 10.1038/s41598-017-16827-y 10.1016/j.neuroimage.2006.01.021 10.1016/j.neuroimage.2016.07.035 10.1016/j.biopsycho.2018.01.003 10.7863/ultra.32.9.1623 10.1126/science.1110324 10.1016/0028-3932(92)90065-T 10.1186/s12916-017-0972-8 10.1016/j.biopsycho.2005.10.003 10.1007/s12264-016-0025-x 10.1006/nimg.1998.0395 10.3390/bs8040039 10.1176/appi.books.9780890425596 10.1177/155005941004100406 10.1016/j.neuroimage.2012.01.021 10.1186/s13229-016-0089-5 10.1016/j.nicl.2017.07.006 10.1002/hbm.21284 10.1503/jpn.150205 10.1016/j.biopsych.2017.01.016 10.1017/thg.2012.13 10.1073/pnas.1718418115 10.1111/1469-8986.00011 10.1016/j.ijpsycho.2005.02.008 10.1016/j.biopsycho.2008.07.008 10.1093/cercor/bhp026 10.1111/cns.12835 10.1080/01621459.1987.10478551 10.7554/eLife.22784 10.1038/mp.2016.60 10.1016/S0925-4927(00)00067-6 10.1002/dev.21119 10.1007/s11682-017-9718-7 10.1371/journal.pone.0101165 10.1016/j.jpsychires.2012.08.003 10.1097/NMD.0b013e3181594cb7 10.1038/s41398-017-0005-6 10.1523/JNEUROSCI.3692-13.2014 10.3389/fnhum.2014.00877 10.1016/j.neubiorev.2017.04.021 10.1093/cercor/bhq179 10.1523/JNEUROSCI.5285-03.2004 10.1017/S0048577298000134 10.1007/s00702-015-1432-2 10.3389/neuro.11.033.2009 10.1016/j.ebiom.2017.06.013 |
| ContentType | Journal Article |
| Copyright | Copyright © 2019 by the American Psychiatric Association 2019 Copyright American Psychiatric Association Dec 2019 |
| Copyright_xml | – notice: Copyright © 2019 by the American Psychiatric Association 2019 – notice: Copyright American Psychiatric Association Dec 2019 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM K9. NAPCQ 7X8 5PM |
| DOI | 10.1176/appi.ajp.2019.18101144 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic ProQuest Health & Medical Complete (Alumni) MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1535-7228 |
| EndPage | 1049 |
| ExternalDocumentID | PMC12038721 31352813 10_1176_appi_ajp_2019_18101144 10.1176/appi.ajp.2019.18101144 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: Wellcome Trust – fundername: Medical Research Council grantid: MR/K022202 – fundername: NIBIB NIH HHS grantid: U54 EB020403 – fundername: NIMH NIH HHS grantid: R01 MH085734 – fundername: NIMH NIH HHS grantid: R37 MH101495 – fundername: NIMH NIH HHS grantid: K23 MH090421 – fundername: Medical Research Council grantid: MR/K022202/1 – fundername: Medical Research Council grantid: G0802594 – fundername: NCRR NIH HHS grantid: P41 RR008079 – fundername: NIMH NIH HHS grantid: R01 MH059259 |
| GroupedDBID | - 1AW 1HT 1QT 23M 2J7 2WC 53G 55 5GY 5RE 85S 8R4 8R5 AAIKC AAPBV AAWTL ABFLS ABIVO ABPPZ ABPTK ABUFD ABZEH ACGOD ACHQT ACNCT ACVYA ADACO ADBBV ADBIT ADCOW AENEX AGNAY AHMBA ALMA_UNASSIGNED_HOLDINGS ASUFR BAJDF BAWUL CS3 DIK DZ E3Z EBS EX3 F5P FH7 FJW G0H GX1 HZ L7B MVM N9A NHB P2P PQEST PQQKQ Q2X RAY RXW RYA S10 SJN TAE TWZ UHB UKR ULE UPT WH7 WOQ WOW X X4V X6Y X7M XJT XZL YRY YZZ Z ZA5 ZHY ZY1 --- --Z -DZ -~X .55 4.4 6J9 7K8 AAJMC AAMNW AAWTO AAYXX ACBMB ACGFO ADMHG AFAZI AFOSN AGHSJ CITATION F8P H13 HF~ HZ~ OK1 Q.- TEORI TR2 VVN XSW YFH YOC YSK YWH ZCA ZRR CGR CUY CVF ECM EIF NPM K9. NAPCQ 7X8 ADXHL 5PM EJD |
| ID | FETCH-LOGICAL-a487t-9d8dfadcd104af385d6d3450e3314a66460df7f277c742c4f393ab134bb86f6d3 |
| ISSN | 0002-953X 1535-7228 |
| IngestDate | Thu Aug 21 18:26:41 EDT 2025 Fri Sep 05 13:29:36 EDT 2025 Sun Jun 29 12:51:37 EDT 2025 Sat May 31 02:10:46 EDT 2025 Thu Apr 24 22:56:18 EDT 2025 Tue Jul 01 04:09:11 EDT 2025 Tue Jan 05 19:03:45 EST 2021 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | Left-Right Asymmetry Laterality MRI Major Depressive Disorder |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-a487t-9d8dfadcd104af385d6d3450e3314a66460df7f277c742c4f393ab134bb86f6d3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.2019.18101144 |
| PMID | 31352813 |
| PQID | 2322647765 |
| PQPubID | 40661 |
| PageCount | 11 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_12038721 proquest_miscellaneous_2266337622 proquest_journals_2322647765 pubmed_primary_31352813 crossref_citationtrail_10_1176_appi_ajp_2019_18101144 crossref_primary_10_1176_appi_ajp_2019_18101144 appi_journals_10_1176_appi_ajp_2019_18101144 |
| ProviderPackageCode | RAY RYA X4V 1QT BAJDF G0H CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2019-12-01 |
| PublicationDateYYYYMMDD | 2019-12-01 |
| PublicationDate_xml | – month: 12 year: 2019 text: 2019-12-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Washington |
| PublicationTitle | The American journal of psychiatry |
| PublicationTitleAlternate | Am J Psychiatry |
| PublicationYear | 2019 |
| Publisher | American Psychiatric Association |
| Publisher_xml | – name: American Psychiatric Association |
| References | Moinfar, Z 2017; 6 Agcaoglu, O 2018; 12 Tenke, CE 2010; 41 Vollebregt, MA 2017; 16 Bansal, R 2012; 33 Sweeney, JA 2018; 24 Trinkl, M 2018; 132 van Erp, TG 2016; 21 Davidson, RJ 1998; 35 Liu, H 2018; 7 Koo, PC 2017; 124 Zhao, Y 2017; 21 Zhang, FF 2018; 24 Dougherty, CC 2016; 7 Abu-Rustum, SE 2013; 32 de Moraes, H 2008; 79 Lisgo, S 2017; 82 Fusee, W 2012; 46 Mazoyer, B 2018; 223 Liu, W 2016; 32 Lavretsky, H 2000; 100 Hepper, PG 2013; 55 Pompeu, FAMS 2008; 79 Schmaal, L 2016; 21 Bansal, R 2014; 34 Thome, J 2017; 124 Verduijn, J 2017; 15 Coan, JA 2006; 72 Milaneschi, Y 2017; 15 Kumar, A 2000; 100 Cohn, JF 2006; 59 Fennema-Notestine, C 2009; 19 Veltman, DJ 2016; 21 Keshavan, A 2016; 142 Bitsika, V 2015; 292 Deslandes, AC 2008; 79 Batista-García-Ramó, K 2018; 8 Mao, Y 2016; 32 Blier, P 2012; 46 Allen, JJ 2006; 72 Raballo, R 2004; 24 Abu-Khalil, A 2005; 308 Cohen, MM 2007; 195 Tenke, CE 2012; 33 Iglewicz, B 1987; 82 Bruder, GE 2017; 78 Stewart, JW 2017; 78 Hugdahl, K 2014; 34 Karlebach, G 2017; 82 Guadalupe, T 2017; 11 de Kovel, CGF 2017; 82 Chen, C 2014; 8 Langs, G 2011; 21 Coan, JA 2003; 40 Desikan, RS 2006; 31 Korada, S 2004; 24 McGrath, PJ 2017; 78 Sun, X 2019; 189 Damaraju, E 2018; 12 Fischl, B 2012; 62 Hibar, DP 2017; 22 Jaworska, N 2012; 46 van Putten, MJAM 2017; 16 Shin, DM 2004; 24 Kong, X-Z 2018; 115 Costafreda, SG 2009; 3 Eyler, LT 2009; 19 Kessler, RC 2013; 34 Wei, D 2016; 32 Sereno, MI 1999; 9 Grünewald, BD 2018; 132 Mathias, SR 2018; 115 Plessen, KJ 2014; 34 Bruder, GE 2012; 33 Dale, AM 1999; 9 Sun, T 2005; 308 Peng, W 2018; 24 Jobard, G 2014; 9 Albert, PR 2015; 40 Parma, V 2017; 7 Bromet, EJ 2013; 34 Romans, SE 2007; 195 Jesulola, E 2015; 292 Ziade, MF 2013; 32 Chen, L 2017; 21 Brasselet, R 2017; 7 McKnight, PE 2006; 72 Katuwal, GJ 2016; 7 Mathias, SR 2017; 11 Guadalupe, T 2018; 115 Crivello, F 2018; 223 Evans, DW 2016; 7 Panizzon, MS 2009; 19 Schmaal, L 2017; 22 Allen, JJ 2003; 40 vanErp, TGM 2017; 11 Zhang, W 2017; 21 Omiya, Y 2014; 8 Si, T 2019; 189 Mazoyer, B 2014; 9 Abu-Rustum, RS 2013; 32 Fischl, B 1999; 9 Sämann, PG 2017; 22 Brugger, PC 2011; 21 Rentería, ME 2012; 15 Schmitz, J 2017; 6 Bilker, W 2000; 100 Berger, C 2017; 124 Ocklenburg, S 2017; 6 Patoine, C 2005; 308 van der Vinne, N 2017; 16 Miller, R 2018; 12 Sharpley, CF 2015; 292 Tzourio-Mazoyer, N 2018; 223 Vuga, M 2006; 59 Fox, NAF 2006; 59 Wysocki, CJ 1992; 30 Tyas, J 2007; 195 Schmidt, P 2016; 142 Xia, M 2019; 189 Hoaglin, DC 1987; 82 Du, L 2018; 7 Gates, NA 2010; 41 Biberacher, V 2016; 142 Manna, CB 2010; 41 Du, W 2018; 7 Fernández-Verdecia, CI 2018; 8 Zago, L 2014; 9 Verhoeven, JE 2017; 15 Greimel, E 2018; 132 Ségonne, F 2006; 31 Zoia, S 2017; 7 Gilbert, AN 1992; 30 Kasprian, G 2011; 21 Fischl, B 2006; 31 B20 B21 B22 B23 B24 B25 B26 B27 B28 B29 B30 B32 B33 B34 B35 B37 B39 B1 B2 B3 B4 B5 B6 B7 B8 B9 Tzourio-Mazoyer N (B36) 2018; 223 B40 B41 B42 B43 B44 B45 B46 B47 B48 B49 B50 B51 B52 B53 B10 B54 B11 B12 B13 B14 B15 B16 B17 B18 B19 Chambers JM (B31) 1992 |
| References_xml | – volume: 195 start-page: 905 year: 2007 end-page: 911 article-title: Gender differences in the symptoms of major depressive disorder publication-title: J Nerv Ment Dis – volume: 115 start-page: E5154 year: 2018 end-page: E5163 article-title: Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium publication-title: Proc Natl Acad Sci USA – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 223 start-page: 1217 year: 2018 end-page: 1228 article-title: Is the planum temporale surface area a marker of hemispheric or regional language lateralization? publication-title: Brain Struct Funct – volume: 24 start-page: 2247 year: 2004 end-page: 2258 article-title: Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice publication-title: J Neurosci – volume: 3 start-page: 33 year: 2009 article-title: Pooling fMRI data: meta-analysis, mega-analysis, and multi-center studies publication-title: Front Neuroinform – volume: 33 start-page: 1325 year: 2012 end-page: 1333 article-title: Relationship of resting EEG with anatomical MRI measures in individuals at high and low risk for depression publication-title: Hum Brain Mapp – volume: 40 start-page: 219 year: 2015 end-page: 221 article-title: Why is depression more prevalent in women? publication-title: J Psychiatry Neurosci – volume: 7 start-page: 16804 year: 2017 article-title: The origin of human handedness and its role in pre-birth motor control publication-title: Sci Rep – volume: 223 start-page: 1217 year: 2018 end-page: 1228 article-title: Is the planum temporale surface area a marker of hemispheric or regional language lateralization? publication-title: Brain Struct Funct – volume: 32 start-page: 217 year: 2016 end-page: 226 article-title: Structural asymmetry of dorsolateral prefrontal cortex correlates with depressive symptoms: evidence from healthy individuals and patients with major depressive disorder publication-title: Neurosci Bull – volume: 33 start-page: 1325 year: 2012 end-page: 1333 article-title: Relationship of resting EEG with anatomical MRI measures in individuals at high and low risk for depression publication-title: Hum Brain Mapp – volume: 7 start-page: 3 year: 2018 article-title: Stimulated left DLPFC–nucleus accumbens functional connectivity predicts the anti-depression and anti-anxiety effects of rTMS for depression publication-title: Transl Psychiatry – volume: 19 start-page: 2728 year: 2009 end-page: 2735 article-title: Distinct genetic influences on cortical surface area and cortical thickness publication-title: Cereb Cortex – volume: 78 start-page: 178 year: 2017 end-page: 191 article-title: Right brain, left brain in depressive disorders: clinical and theoretical implications of behavioral, electrophysiological, and neuroimaging findings publication-title: Neurosci Biobehav Rev – volume: 30 start-page: 601 year: 1992 end-page: 608 article-title: Hand preference and age in the United States publication-title: Neuropsychologia – volume: 32 start-page: 217 year: 2016 end-page: 226 article-title: Structural asymmetry of dorsolateral prefrontal cortex correlates with depressive symptoms: evidence from healthy individuals and patients with major depressive disorder publication-title: Neurosci Bull – volume: 7 start-page: 16804 year: 2017 article-title: The origin of human handedness and its role in pre-birth motor control publication-title: Sci Rep – volume: 24 start-page: 2247 year: 2004 end-page: 2258 article-title: Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice publication-title: J Neurosci – volume: 21 start-page: 228 year: 2017 end-page: 235 article-title: Gray matter abnormalities in non-comorbid medication-naive patients with major depressive disorder or social anxiety disorder publication-title: EBioMedicine – volume: 189 start-page: 700 year: 2019 end-page: 714 article-title: Reproducibility of functional brain alterations in major depressive disorder: evidence from a multisite resting-state functional MRI study with 1,434 individuals publication-title: Neuroimage – volume: 41 start-page: 196 year: 2010 end-page: 202 article-title: EEG hemispheric asymmetries during cognitive tasks in depressed patients with high versus low trait anxiety publication-title: Clin EEG Neurosci – volume: 189 start-page: 700 year: 2019 end-page: 714 article-title: Reproducibility of functional brain alterations in major depressive disorder: evidence from a multisite resting-state functional MRI study with 1,434 individuals publication-title: Neuroimage – volume: 15 start-page: 215 year: 2017 article-title: Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule publication-title: BMC Med – volume: 24 start-page: 994 year: 2018 end-page: 1003 article-title: Brain structure alterations in depression: psychoradiological evidence publication-title: CNS Neurosci Ther – volume: 16 start-page: 79 year: 2017 end-page: 87 article-title: Frontal alpha asymmetry as a diagnostic marker in depression: fact or fiction? A meta-analysis publication-title: Neuroimage Clin – volume: 32 start-page: 1623 year: 2013 end-page: 1629 article-title: Reference values for the right and left fetal choroid plexus at 11 to 13 weeks: an early sign of “developmental” laterality? publication-title: J Ultrasound Med – volume: 21 start-page: 1076 year: 2011 end-page: 1083 article-title: The prenatal origin of hemispheric asymmetry: an in utero neuroimaging study publication-title: Cereb Cortex – volume: 79 start-page: 317 year: 2008 end-page: 322 article-title: Electroencephalographic frontal asymmetry and depressive symptoms in the elderly publication-title: Biol Psychol – volume: 8 start-page: 877 year: 2014 article-title: Brain asymmetry in cortical thickness is correlated with cognitive function publication-title: Front Hum Neurosci – volume: 7 start-page: 28 year: 2016 article-title: Asymmetry of fusiform structure in autism spectrum disorder: trajectory and association with symptom severity publication-title: Mol Autism – volume: 34 start-page: 6294 year: 2014 end-page: 6302 article-title: Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span publication-title: J Neurosci – volume: 72 start-page: 198 year: 2006 end-page: 207 article-title: A capability model of individual differences in frontal EEG asymmetry publication-title: Biol Psychol – volume: 6 year: 2017 article-title: Epigenetic regulation of lateralized fetal spinal gene expression underlies hemispheric asymmetries publication-title: eLife – volume: 78 start-page: 178 year: 2017 end-page: 191 article-title: Right brain, left brain in depressive disorders: clinical and theoretical implications of behavioral, electrophysiological, and neuroimaging findings publication-title: Neurosci Biobehav Rev – volume: 40 start-page: 106 year: 2003 end-page: 114 article-title: Frontal EEG asymmetry and the behavioral activation and inhibition systems publication-title: Psychophysiology – volume: 9 year: 2014 article-title: Gaussian mixture modeling of hemispheric lateralization for language in a large sample of healthy individuals balanced for handedness publication-title: PLoS One – volume: 9 start-page: 179 year: 1999 end-page: 194 article-title: Cortical surface-based analysis, I: segmentation and surface reconstruction publication-title: Neuroimage – volume: 9 start-page: 179 year: 1999 end-page: 194 article-title: Cortical surface-based analysis, I: segmentation and surface reconstruction publication-title: Neuroimage – volume: 62 start-page: 774 year: 2012 end-page: 781 article-title: FreeSurfer publication-title: Neuroimage – volume: 8 start-page: 877 year: 2014 article-title: Brain asymmetry in cortical thickness is correlated with cognitive function publication-title: Front Hum Neurosci – volume: 292 start-page: 56 year: 2015 end-page: 67 article-title: Frontal alpha asymmetry as a pathway to behavioural withdrawal in depression: research findings and issues publication-title: Behav Brain Res – volume: 34 start-page: 6294 year: 2014 end-page: 6302 article-title: Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span publication-title: J Neurosci – volume: 292 start-page: 56 year: 2015 end-page: 67 article-title: Frontal alpha asymmetry as a pathway to behavioural withdrawal in depression: research findings and issues publication-title: Behav Brain Res – volume: 115 start-page: E5154 year: 2018 end-page: E5163 article-title: Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium publication-title: Proc Natl Acad Sci USA – volume: 16 start-page: 79 year: 2017 end-page: 87 article-title: Frontal alpha asymmetry as a diagnostic marker in depression: fact or fiction? A meta-analysis publication-title: Neuroimage Clin – volume: 195 start-page: 905 year: 2007 end-page: 911 article-title: Gender differences in the symptoms of major depressive disorder publication-title: J Nerv Ment Dis – volume: 9 start-page: 179 year: 1999 end-page: 194 article-title: Cortical surface-based analysis, I: segmentation and surface reconstruction publication-title: Neuroimage – volume: 72 start-page: 198 year: 2006 end-page: 207 article-title: A capability model of individual differences in frontal EEG asymmetry publication-title: Biol Psychol – volume: 21 start-page: 228 year: 2017 end-page: 235 article-title: Gray matter abnormalities in non-comorbid medication-naive patients with major depressive disorder or social anxiety disorder publication-title: EBioMedicine – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 16 start-page: 79 year: 2017 end-page: 87 article-title: Frontal alpha asymmetry as a diagnostic marker in depression: fact or fiction? A meta-analysis publication-title: Neuroimage Clin – volume: 32 start-page: 1623 year: 2013 end-page: 1629 article-title: Reference values for the right and left fetal choroid plexus at 11 to 13 weeks: an early sign of “developmental” laterality? publication-title: J Ultrasound Med – volume: 21 start-page: 228 year: 2017 end-page: 235 article-title: Gray matter abnormalities in non-comorbid medication-naive patients with major depressive disorder or social anxiety disorder publication-title: EBioMedicine – volume: 7 start-page: 16804 year: 2017 article-title: The origin of human handedness and its role in pre-birth motor control publication-title: Sci Rep – volume: 308 start-page: 1794 year: 2005 end-page: 1798 article-title: Early asymmetry of gene transcription in embryonic human left and right cerebral cortex publication-title: Science – volume: 21 start-page: 806 year: 2016 end-page: 812 article-title: Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 30 start-page: 601 year: 1992 end-page: 608 article-title: Hand preference and age in the United States publication-title: Neuropsychologia – volume: 59 start-page: 107 year: 2006 end-page: 115 article-title: Long-term stability of frontal electroencephalographic asymmetry in adults with a history of depression and controls publication-title: Int J Psychophysiol – volume: 21 start-page: 1076 year: 2011 end-page: 1083 article-title: The prenatal origin of hemispheric asymmetry: an in utero neuroimaging study publication-title: Cereb Cortex – volume: 12 start-page: 615 year: 2018 end-page: 630 article-title: Decreased hemispheric connectivity and decreased intra- and inter- hemisphere asymmetry of resting state functional network connectivity in schizophrenia publication-title: Brain Imaging Behav – volume: 82 start-page: 1147 year: 1987 end-page: 1149 article-title: Fine-tuning some resistant rules for outlier labeling publication-title: J Am Stat Assoc – volume: 7 start-page: 3 year: 2018 article-title: Stimulated left DLPFC–nucleus accumbens functional connectivity predicts the anti-depression and anti-anxiety effects of rTMS for depression publication-title: Transl Psychiatry – volume: 223 start-page: 1217 year: 2018 end-page: 1228 article-title: Is the planum temporale surface area a marker of hemispheric or regional language lateralization? publication-title: Brain Struct Funct – volume: 7 start-page: 28 year: 2016 article-title: Asymmetry of fusiform structure in autism spectrum disorder: trajectory and association with symptom severity publication-title: Mol Autism – volume: 6 year: 2017 article-title: Epigenetic regulation of lateralized fetal spinal gene expression underlies hemispheric asymmetries publication-title: eLife – volume: 195 start-page: 905 year: 2007 end-page: 911 article-title: Gender differences in the symptoms of major depressive disorder publication-title: J Nerv Ment Dis – volume: 132 start-page: 212 year: 2018 end-page: 216 article-title: Resting frontal EEG asymmetry patterns in adolescents with and without major depression publication-title: Biol Psychol – volume: 11 start-page: 1497 year: 2017 end-page: 1514 article-title: Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex publication-title: Brain Imaging Behav – volume: 115 start-page: E5154 year: 2018 end-page: E5163 article-title: Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium publication-title: Proc Natl Acad Sci USA – volume: 33 start-page: 1325 year: 2012 end-page: 1333 article-title: Relationship of resting EEG with anatomical MRI measures in individuals at high and low risk for depression publication-title: Hum Brain Mapp – volume: 308 start-page: 1794 year: 2005 end-page: 1798 article-title: Early asymmetry of gene transcription in embryonic human left and right cerebral cortex publication-title: Science – volume: 41 start-page: 196 year: 2010 end-page: 202 article-title: EEG hemispheric asymmetries during cognitive tasks in depressed patients with high versus low trait anxiety publication-title: Clin EEG Neurosci – volume: 79 start-page: 317 year: 2008 end-page: 322 article-title: Electroencephalographic frontal asymmetry and depressive symptoms in the elderly publication-title: Biol Psychol – volume: 12 start-page: 615 year: 2018 end-page: 630 article-title: Decreased hemispheric connectivity and decreased intra- and inter- hemisphere asymmetry of resting state functional network connectivity in schizophrenia publication-title: Brain Imaging Behav – volume: 308 start-page: 1794 year: 2005 end-page: 1798 article-title: Early asymmetry of gene transcription in embryonic human left and right cerebral cortex publication-title: Science – volume: 82 start-page: 204 year: 2017 end-page: 212 article-title: Left-right asymmetry of maturation rates in human embryonic neural development publication-title: Biol Psychiatry – volume: 22 start-page: 900 year: 2017 end-page: 909 article-title: Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 32 start-page: 1623 year: 2013 end-page: 1629 article-title: Reference values for the right and left fetal choroid plexus at 11 to 13 weeks: an early sign of “developmental” laterality? publication-title: J Ultrasound Med – volume: 124 start-page: 109 year: 2017 end-page: 118 article-title: Current source density analysis of resting state EEG in depression: a review publication-title: J Neural Transm (Vienna) – volume: 46 start-page: 1483 year: 2012 end-page: 1491 article-title: α Power, α asymmetry, and anterior cingulate cortex activity in depressed males and females publication-title: J Psychiatr Res – volume: 21 start-page: 806 year: 2016 end-page: 812 article-title: Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 78 start-page: 178 year: 2017 end-page: 191 article-title: Right brain, left brain in depressive disorders: clinical and theoretical implications of behavioral, electrophysiological, and neuroimaging findings publication-title: Neurosci Biobehav Rev – volume: 11 start-page: 1497 year: 2017 end-page: 1514 article-title: Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex publication-title: Brain Imaging Behav – volume: 34 start-page: 6294 year: 2014 end-page: 6302 article-title: Sex, age, and cognitive correlates of asymmetries in thickness of the cortical mantle across the life span publication-title: J Neurosci – volume: 11 start-page: 1497 year: 2017 end-page: 1514 article-title: Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex publication-title: Brain Imaging Behav – volume: 24 start-page: 994 year: 2018 end-page: 1003 article-title: Brain structure alterations in depression: psychoradiological evidence publication-title: CNS Neurosci Ther – volume: 31 start-page: 968 year: 2006 end-page: 980 article-title: An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest publication-title: Neuroimage – volume: 142 start-page: 188 year: 2016 end-page: 197 article-title: Intra- and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis publication-title: Neuroimage – volume: 59 start-page: 107 year: 2006 end-page: 115 article-title: Long-term stability of frontal electroencephalographic asymmetry in adults with a history of depression and controls publication-title: Int J Psychophysiol – volume: 19 start-page: 2728 year: 2009 end-page: 2735 article-title: Distinct genetic influences on cortical surface area and cortical thickness publication-title: Cereb Cortex – volume: 142 start-page: 188 year: 2016 end-page: 197 article-title: Intra- and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis publication-title: Neuroimage – volume: 82 start-page: 1147 year: 1987 end-page: 1149 article-title: Fine-tuning some resistant rules for outlier labeling publication-title: J Am Stat Assoc – volume: 21 start-page: 806 year: 2016 end-page: 812 article-title: Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 24 start-page: 994 year: 2018 end-page: 1003 article-title: Brain structure alterations in depression: psychoradiological evidence publication-title: CNS Neurosci Ther – volume: 21 start-page: 1076 year: 2011 end-page: 1083 article-title: The prenatal origin of hemispheric asymmetry: an in utero neuroimaging study publication-title: Cereb Cortex – volume: 34 start-page: 119 year: 2013 end-page: 138 article-title: The epidemiology of depression across cultures publication-title: Annu Rev Public Health – volume: 59 start-page: 107 year: 2006 end-page: 115 article-title: Long-term stability of frontal electroencephalographic asymmetry in adults with a history of depression and controls publication-title: Int J Psychophysiol – volume: 132 start-page: 212 year: 2018 end-page: 216 article-title: Resting frontal EEG asymmetry patterns in adolescents with and without major depression publication-title: Biol Psychol – volume: 142 start-page: 188 year: 2016 end-page: 197 article-title: Intra- and interscanner variability of magnetic resonance imaging based volumetry in multiple sclerosis publication-title: Neuroimage – volume: 15 start-page: 215 year: 2017 article-title: Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule publication-title: BMC Med – volume: 46 start-page: 1483 year: 2012 end-page: 1491 article-title: α Power, α asymmetry, and anterior cingulate cortex activity in depressed males and females publication-title: J Psychiatr Res – volume: 100 start-page: 41 year: 2000 end-page: 47 article-title: Volumetric asymmetries in late-onset mood disorders: an attenuation of frontal asymmetry with depression severity publication-title: Psychiatry Res – volume: 12 start-page: 615 year: 2018 end-page: 630 article-title: Decreased hemispheric connectivity and decreased intra- and inter- hemisphere asymmetry of resting state functional network connectivity in schizophrenia publication-title: Brain Imaging Behav – volume: 292 start-page: 56 year: 2015 end-page: 67 article-title: Frontal alpha asymmetry as a pathway to behavioural withdrawal in depression: research findings and issues publication-title: Behav Brain Res – volume: 55 start-page: 588 year: 2013 end-page: 595 article-title: The developmental origins of laterality: fetal handedness publication-title: Dev Psychobiol – volume: 19 start-page: 2728 year: 2009 end-page: 2735 article-title: Distinct genetic influences on cortical surface area and cortical thickness publication-title: Cereb Cortex – volume: 124 start-page: 109 year: 2017 end-page: 118 article-title: Current source density analysis of resting state EEG in depression: a review publication-title: J Neural Transm (Vienna) – volume: 72 start-page: 198 year: 2006 end-page: 207 article-title: A capability model of individual differences in frontal EEG asymmetry publication-title: Biol Psychol – volume: 22 start-page: 900 year: 2017 end-page: 909 article-title: Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 32 start-page: 217 year: 2016 end-page: 226 article-title: Structural asymmetry of dorsolateral prefrontal cortex correlates with depressive symptoms: evidence from healthy individuals and patients with major depressive disorder publication-title: Neurosci Bull – volume: 24 start-page: 2247 year: 2004 end-page: 2258 article-title: Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice publication-title: J Neurosci – volume: 6 year: 2017 article-title: Epigenetic regulation of lateralized fetal spinal gene expression underlies hemispheric asymmetries publication-title: eLife – volume: 82 start-page: 204 year: 2017 end-page: 212 article-title: Left-right asymmetry of maturation rates in human embryonic neural development publication-title: Biol Psychiatry – volume: 34 start-page: 119 year: 2013 end-page: 138 article-title: The epidemiology of depression across cultures publication-title: Annu Rev Public Health – volume: 41 start-page: 196 year: 2010 end-page: 202 article-title: EEG hemispheric asymmetries during cognitive tasks in depressed patients with high versus low trait anxiety publication-title: Clin EEG Neurosci – volume: 79 start-page: 317 year: 2008 end-page: 322 article-title: Electroencephalographic frontal asymmetry and depressive symptoms in the elderly publication-title: Biol Psychol – volume: 82 start-page: 204 year: 2017 end-page: 212 article-title: Left-right asymmetry of maturation rates in human embryonic neural development publication-title: Biol Psychiatry – volume: 100 start-page: 41 year: 2000 end-page: 47 article-title: Volumetric asymmetries in late-onset mood disorders: an attenuation of frontal asymmetry with depression severity publication-title: Psychiatry Res – volume: 8 year: 2018 article-title: What we know about the brain structure-function relationship publication-title: Behav Sci (Basel) – volume: 9 year: 2014 article-title: Gaussian mixture modeling of hemispheric lateralization for language in a large sample of healthy individuals balanced for handedness publication-title: PLoS One – volume: 46 start-page: 1483 year: 2012 end-page: 1491 article-title: α Power, α asymmetry, and anterior cingulate cortex activity in depressed males and females publication-title: J Psychiatr Res – volume: 40 start-page: 106 year: 2003 end-page: 114 article-title: Frontal EEG asymmetry and the behavioral activation and inhibition systems publication-title: Psychophysiology – volume: 8 year: 2018 article-title: What we know about the brain structure-function relationship publication-title: Behav Sci (Basel) – volume: 9 year: 2014 article-title: Gaussian mixture modeling of hemispheric lateralization for language in a large sample of healthy individuals balanced for handedness publication-title: PLoS One – volume: 35 start-page: 607 year: 1998 end-page: 614 article-title: Anterior electrophysiological asymmetries, emotion, and depression: conceptual and methodological conundrums publication-title: Psychophysiology – volume: 100 start-page: 41 year: 2000 end-page: 47 article-title: Volumetric asymmetries in late-onset mood disorders: an attenuation of frontal asymmetry with depression severity publication-title: Psychiatry Res – volume: 189 start-page: 700 year: 2019 end-page: 714 article-title: Reproducibility of functional brain alterations in major depressive disorder: evidence from a multisite resting-state functional MRI study with 1,434 individuals publication-title: Neuroimage – volume: 15 start-page: 215 year: 2017 article-title: Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule publication-title: BMC Med – volume: 7 start-page: 28 year: 2016 article-title: Asymmetry of fusiform structure in autism spectrum disorder: trajectory and association with symptom severity publication-title: Mol Autism – volume: 132 start-page: 212 year: 2018 end-page: 216 article-title: Resting frontal EEG asymmetry patterns in adolescents with and without major depression publication-title: Biol Psychol – volume: 7 start-page: 3 year: 2018 article-title: Stimulated left DLPFC–nucleus accumbens functional connectivity predicts the anti-depression and anti-anxiety effects of rTMS for depression publication-title: Transl Psychiatry – volume: 22 start-page: 900 year: 2017 end-page: 909 article-title: Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group publication-title: Mol Psychiatry – volume: 15 start-page: 401 year: 2012 end-page: 413 article-title: Cerebral asymmetry: a quantitative, multifactorial, and plastic brain phenotype publication-title: Twin Res Hum Genet – volume: 124 start-page: 109 year: 2017 end-page: 118 article-title: Current source density analysis of resting state EEG in depression: a review publication-title: J Neural Transm (Vienna) – ident: B3 doi: 10.1146/annurev-publhealth-031912-114409 – ident: B6 doi: 10.1038/mp.2015.69 – ident: B15 doi: 10.1016/j.bbr.2015.05.058 – ident: B23 doi: 10.1007/s11682-016-9629-z – volume-title: Statistical Models in S year: 1992 ident: B31 – ident: B44 doi: 10.1016/j.neuroimage.2019.01.074 – ident: B46 doi: 10.1038/s41598-017-16827-y – ident: B27 doi: 10.1016/j.neuroimage.2006.01.021 – ident: B5 doi: 10.1016/j.neuroimage.2016.07.035 – ident: B14 doi: 10.1016/j.biopsycho.2018.01.003 – ident: B47 doi: 10.7863/ultra.32.9.1623 – ident: B51 doi: 10.1126/science.1110324 – ident: B53 doi: 10.1016/0028-3932(92)90065-T – ident: B2 doi: 10.1186/s12916-017-0972-8 – ident: B42 doi: 10.1016/j.biopsycho.2005.10.003 – ident: B21 doi: 10.1007/s12264-016-0025-x – volume: 223 start-page: 1217 year: 2018 ident: B36 publication-title: Brain Struct Funct – ident: B28 doi: 10.1006/nimg.1998.0395 – ident: B37 doi: 10.3390/bs8040039 – ident: B1 doi: 10.1176/appi.books.9780890425596 – ident: B43 doi: 10.1177/155005941004100406 – ident: B29 doi: 10.1016/j.neuroimage.2012.01.021 – ident: B9 doi: 10.1186/s13229-016-0089-5 – ident: B16 doi: 10.1016/j.nicl.2017.07.006 – ident: B40 doi: 10.1002/hbm.21284 – ident: B26 doi: 10.1503/jpn.150205 – ident: B49 doi: 10.1016/j.biopsych.2017.01.016 – ident: B10 doi: 10.1017/thg.2012.13 – ident: B24 doi: 10.1073/pnas.1718418115 – ident: B19 doi: 10.1111/1469-8986.00011 – ident: B13 doi: 10.1016/j.ijpsycho.2005.02.008 – ident: B12 doi: 10.1016/j.biopsycho.2008.07.008 – ident: B32 doi: 10.1093/cercor/bhp026 – ident: B4 doi: 10.1111/cns.12835 – ident: B30 doi: 10.1080/01621459.1987.10478551 – ident: B50 doi: 10.7554/eLife.22784 – ident: B7 doi: 10.1038/mp.2016.60 – ident: B22 doi: 10.1016/S0925-4927(00)00067-6 – ident: B45 doi: 10.1002/dev.21119 – ident: B8 doi: 10.1007/s11682-017-9718-7 – ident: B52 doi: 10.1371/journal.pone.0101165 – ident: B11 doi: 10.1016/j.jpsychires.2012.08.003 – ident: B25 doi: 10.1097/NMD.0b013e3181594cb7 – ident: B17 doi: 10.1038/s41398-017-0005-6 – ident: B35 doi: 10.1523/JNEUROSCI.3692-13.2014 – ident: B34 doi: 10.3389/fnhum.2014.00877 – ident: B18 doi: 10.1016/j.neubiorev.2017.04.021 – ident: B48 doi: 10.1093/cercor/bhq179 – ident: B39 doi: 10.1523/JNEUROSCI.5285-03.2004 – ident: B20 doi: 10.1017/S0048577298000134 – ident: B41 doi: 10.1007/s00702-015-1432-2 – ident: B54 doi: 10.3389/neuro.11.033.2009 – ident: B33 doi: 10.1016/j.ebiom.2017.06.013 |
| SSID | ssj0000372 |
| Score | 2.504833 |
| Snippet | Objective:Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle... Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle... Objective: Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown... Magnetic resonance imaging (MRI) studies have shown subtle differences of brain anatomy between people with major depressive disorder (MDD) and healthy... |
| SourceID | pubmedcentral proquest pubmed crossref appi |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1039 |
| SubjectTerms | Adult Antidepressants Anxiety Asymmetry Brain Brain - anatomy & histology Case-Control Studies Databases, Factual - statistics & numerical data Depressive Disorder, Major - pathology Dominance, Cerebral Female Humans Magnetic Resonance Imaging Male Mental depression Meta-Analysis as Topic Neuroimaging Young Adult |
| Title | No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis |
| URI | http://dx.doi.org/10.1176/appi.ajp.2019.18101144 https://www.ncbi.nlm.nih.gov/pubmed/31352813 https://www.proquest.com/docview/2322647765 https://www.proquest.com/docview/2266337622 https://pubmed.ncbi.nlm.nih.gov/PMC12038721 |
| Volume | 176 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLbKkBAviPsCAxmJN0gXx7nylqGxjdGKh07aWxTnonVqk2lrkcbP5Zdwji9J2lUq4yWq7NhJfb7Y59jfOYeQj6AUwyrOItsv88j2QKG2hR-Gdg7KeZY5URF56I08GgfHZ973c_98MPjTYy0tF2KY_97oV_I_UoUykCt6yd5Dsm2nUAC_Qb5wBQnD9Z9kPG4-JTMZFtnQ2Q4w4wMeNS9zFVAjubmdz8vFtXTvG2WXzTVMMYr8ipQhHXtTbw8ejk-ORolM4gla-RT37nXMkr4OO-mcUep-5IlV4rRmx542vxQPQDJLMKfA0bAlEycVqKbKo-zH7VI082lLFU5mpd6bRcqlOs7v1SmnHPsAlmK5L5RA77VmKes9DBav80HMO_80LzrN78Czm8BjX6YQhuXLzNmYkVf7mJtJXWWVMeh1e3M0Hn731nuwR-PNa0kogyhfoU_hJYY2ZfGQYTw0piJWrsXp3tbkAXnohqGiEpycdtoCD11jouEf017s0NP-5n5Ad8CKVT3qjnG0zvHtKU2Tp-SJtnZooqD7jAzK-jl5NNJ8jhfkYtzQHoJpU1GJYNohmLYIplAuEUw7BFOD4C80qanCL-3wSw1-X5Kzb4eTr8e2zv1hZ2BCL-y4iIoqK_ICxJNVPPKLoOCe75ScMy8LAi9wiiqsYETz0HNzr-IxzwTjnhBRUMG9r8hO3dTlLqGVU-YscoICjCGoFjGLhKhArYW1TYAFYZHPOKCp_mBuUmkXh0EqS2H8Uxz_1Iy_RXwz8Gmu4-hjOpfZ1nb7bbsrFUlma4s9I9fu5cACctF5PPAt8qGthjUBD_qyumyWcA9o3Rw0B9e1yGsFg_aRnGE8J8YtEq0ApL0B482v1tTTCxl3nrnIdXHZm_sN2FvyuPvm98gOAKh8B5r8QryXn8JfhuTwmw |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=No+Alterations+of+Brain+Structural+Asymmetry+in+Major+Depressive+Disorder%3A+An+ENIGMA+Consortium+Analysis&rft.jtitle=The+American+journal+of+psychiatry&rft.au=de+Kovel%2C+Carolien+G.F&rft.au=Aftanas%2C+Lyubomir&rft.au=Aleman%2C+Andr%C3%A9&rft.au=Alexander-Bloch%2C+Aaron+F&rft.date=2019-12-01&rft.pub=American+Psychiatric+Association&rft.issn=0002-953X&rft.eissn=1535-7228&rft.volume=176&rft.issue=12&rft.spage=1039&rft.epage=1049&rft_id=info:doi/10.1176%2Fappi.ajp.2019.18101144&rft.externalDocID=10.1176%2Fappi.ajp.2019.18101144 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-953X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-953X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-953X&client=summon |