Microbiome and metabolome association network analysis identifies Clostridium_sensu_stricto_1 as a stronger keystone genus candidate than Bifidobacterium in the gut of common marmosets

• Published in: mSystems Vol. 10; no. 8; p. e0021425
• Main Authors: Hernandez, Jordan B., Hayer, Shivdeep S., Alvarez, Sophie, Fischer, Anne, Hassenstab, Haley R., Cooper, Katherine, Alsafwani, Zahraa W., Benson, Andrew K., Suhr Van Haute, Mallory J., Izard, Jacques, Song, Hyun-Seob, Clayton, Jonathan B.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 07.07.2025
• Subjects: Animals; Bacteria; Bacteroidales; Bifidobacterium; Bile acids; bioinformatics; Captivity; Clostridium; Computational Biology; Diet; Disease; Feces; gut metabolome; gut microbiome; Gut microbiota; Intestinal microflora; marmoset; Metabolism; Metabolites; Metabolomics; Microbiomes; Microbiota; multi-omics; network analysis; Research Article; rRNA 16S; Social isolation; Taurine; Taxonomy; gut metabolome; gut microbiome; non-human primate; bioinformatics; multi-omics; amplicon sequencing; network analysis; marmoset; microbial ecology

Previous studies have identified significant individuality within the gut microbiome of common marmosets. The reasons for this inter-subject variability and how it relates to health in captivity are poorly understood, owing to a lack of knowledge regarding dynamic interactions between specific micro...