Autoimmune Encephalitis in Postpartum Psychosis

• Published in: American Journal of Psychiatry Vol. 172; no. 9; pp. 901 - 908
• Main Authors: Bergink, Veerle, Armangue, Thaís, Titulaer, Maarten J, Markx, Sander, Dalmau, Josep, Kushner, Steven A
• Format: Journal Article
• Language: English
• Published: United States American Psychiatric Association 01.09.2015
• Subjects: Adult; Animals; Autoantibodies - immunology; Brain; Case-Control Studies; Encephalitis; Encephalitis - diagnosis; Encephalitis - etiology; Female; Hashimoto Disease - diagnosis; Hashimoto Disease - etiology; Hippocampus - immunology; Humans; Immunohistochemistry; Postpartum depression; Postpartum Period; Psychosis; Psychotic Disorders - diagnosis; Psychotic Disorders - etiology; Psychotic Disorders - immunology; Puerperal Disorders - diagnosis; Puerperal Disorders - immunology; Rats - immunology; Receptors, N-Methyl-D-Aspartate - immunology; Women; Young Adult

Objective:Significant immunological alterations have been observed in women with first-onset affective psychosis during the postpartum period. Recent studies have highlighted the possibility that a subset of patients with first-onset severe psychiatric episodes might suffer from undiagnosed autoimmu...