Evidence-based point-of-care diagnostics: current status and emerging technologies
Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious dis...
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| Published in | Annual review of analytical chemistry (Palo Alto, Calif.) Vol. 6; p. 191 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.01.2013
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| Subjects | |
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| Abstract | Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious diseases. Early diagnosis and rapid initiation of treatment are crucial in the management of such patients. This review provides the rationale for the use of POC tests in acute coronary syndrome, heart failure, human immunodeficiency virus, and tuberculosis. We also consider emerging technologies that are based on advanced nanomaterials and microfluidics, improved assay sensitivity, miniaturization in device design, reduced costs, and high-throughput multiplex detection, all of which may shape the future development of POC diagnostics. |
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| AbstractList | Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious diseases. Early diagnosis and rapid initiation of treatment are crucial in the management of such patients. This review provides the rationale for the use of POC tests in acute coronary syndrome, heart failure, human immunodeficiency virus, and tuberculosis. We also consider emerging technologies that are based on advanced nanomaterials and microfluidics, improved assay sensitivity, miniaturization in device design, reduced costs, and high-throughput multiplex detection, all of which may shape the future development of POC diagnostics. |
| Author | Renneberg, Reinhard Mak, Wing Cheung Rainer, Timothy H Sin, King Keung Yu, Cheuk Man Chan, Cangel Pui Yee Cheung, Kwan Yee |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23527548$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Acute Coronary Syndrome - diagnosis Cardiovascular Diseases - diagnosis Communicable Diseases - diagnosis Evidence-Based Medicine Heart Failure - diagnosis HIV Infections - diagnosis Humans Microfluidic Analytical Techniques - instrumentation Miniaturization Nanostructures Point-of-Care Systems - trends Tuberculosis - diagnosis |
| Title | Evidence-based point-of-care diagnostics: current status and emerging technologies |
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