Roles of OmpX, an Outer Membrane Protein, on Virulence and Flagellar Expression in Uropathogenic Escherichia coli

• Published in: Infection and immunity Vol. 89; no. 6
• Main Authors: Hirakawa, Hidetada, Suzue, Kazutomo, Takita, Ayako, Kamitani, Wataru, Tomita, Haruyoshi
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 17.05.2021
• Subjects: Molecular Pathogenesis; flagella; pathogenesis; pyelonephritis; virulence; gene regulation; biofilm; motility; urinary tract infection

Uropathogenic Escherichia coli (UPEC) is a major pathogen that causes urinary tract infection (UTI). This bacterium adheres to and internalizes within urinary tract cells, where it aggregates and subsequently forms biofilm-like multicellular colonies that protect UPEC from antimicrobial agents and t...