Accumulation of Macrophages in the CSF of Schizophrenic Patients During Acute Psychotic Episodes

• Published in: The American journal of psychiatry Vol. 156; no. 11; pp. 1725 - 1729
• Main Authors: Nikkil⺯, Heikki V., M�, Kiti, Ahokas, Antti, Miettinen, Kati, Rimón, Ranan, Andersson, Leif C.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Psychiatric Publishing 01.11.1999; American Psychiatric Association
• Subjects: Acute Disease; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Brain; Cell Count; Cells; Cerebrospinal Fluid - cytology; Female; Humans; Lymphocytes - cytology; Macrophages - cytology; Male; Medical sciences; Monocytes - cytology; Nervous system; Pathology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Schizophrenia; Schizophrenia - cerebrospinal fluid; Schizophrenia - diagnosis; Schizophrenic Psychology; Psychosis; Human; Mononuclear cell; Pathophysiology; Pathogenesis; Acute; Central nervous system; Schizophrenia; Cerebrospinal fluid; Brain (vertebrata); Macrophage

OBJECTIVE: There have been numerous reports of organic or structural abnormalities in the central nervous system (CNS) of patients with schizophrenia. Given that pathological conditions in the CNS are frequently reflected in the cell profiles of CSF, the authors compared the cytology of CSF from sch...