Familial Aggregation of Suicide Explained by Cluster B Traits: A Three-Group Family Study of Suicide Controlling for Major Depressive Disorder

• Published in: The American journal of psychiatry Vol. 166; no. 10; pp. 1124 - 1134
• Main Authors: McGirr, Alexander, Alda, Martin, Séguin, Monique, Cabot, Sophie, Lesage, Alain, Turecki, Gustavo
• Format: Journal Article
• Language: English
• Published: Arlington, VA American Psychiatric Association 01.10.2009
• Subjects: Adult; Adult and adolescent clinical studies; Aggression - psychology; Behavior; Biological and medical sciences; Cause of Death; Comorbidity; Data Collection - statistics & numerical data; Depression; Depressive Disorder, Major - epidemiology; Depressive Disorder, Major - genetics; Depressive Disorder, Major - psychology; Family - psychology; Family Health; Female; Genetic Predisposition to Disease - epidemiology; Humans; Impulsive Behavior - diagnosis; Impulsive Behavior - epidemiology; Impulsive Behavior - psychology; Male; Medical sciences; Mental depression; Mental Disorders - epidemiology; Mental Disorders - genetics; Mental Disorders - psychology; Mood disorders; Personality disorders; Personality Disorders - epidemiology; Personality Disorders - genetics; Personality Disorders - psychology; Phenotype; Prevalence; Psychiatric Status Rating Scales; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk Factors; Studies; Suicide; Suicide - psychology; Suicide - statistics & numerical data; Suicides & suicide attempts; Mood disorder; Aggregation; Depression; Suicide; Family study

Objective: There is substantial evidence suggesting that suicide aggregates in families. However, the extent of overlap between the liability to suicide and psychiatric disorders, particularly major depressive disorder, remains an important issue. Similarly, factors that account for the familial tra...