Reduced Evoked Gamma Oscillations in the Frontal Cortex in Schizophrenia Patients: A TMS EEG Study

• Published in: The American journal of psychiatry Vol. 165; no. 8; pp. 996 - 1005
• Main Authors: Ferrarelli, Fabio, Massimini, Marcello, Peterson, Michael J., Riedner, Brady A., Lazar, Mariana, Murphy, Michael J., Huber, Reto, Rosanova, Mario, Alexander, Andrew L., Kalin, Ned, Tononi, Giulio
• Format: Journal Article
• Language: English
• Published: Washington, DC American Psychiatric Association 01.08.2008
• Subjects: Adult; Adult and adolescent clinical studies; Biological and medical sciences; Brain; Brain - anatomy & histology; Brain - physiopathology; Cognitive models; Diagnostic and Statistical Manual of Mental Disorders; Electric fields; Electroencephalography; Female; Frontal Lobe - physiopathology; Gamma rays; Human subjects; Humans; Male; Medical sciences; Neurological disorders; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - physiopathology; Sleep; Transcranial Magnetic Stimulation; Volumetric analysis; Human; Transcranial magnetic stimulation; Motor pathway; Central nervous system; Electrophysiology; Schizophrenia; Electroencephalography; Frontal cortex; Encephalon; Psychosis; Electrodiagnosis; Thalamus; Premotor cortex

Objective: Transcranial magnetic stimulation (TMS) combined with high-density electroencephalography (EEG) can be used to directly examine the properties of thalamocortical circuits in the brain without engaging an individual in cognitive or motor tasks. The authors investigated EEG responses in sch...