Regulation of the Structure of Zirconium-Based Porphyrinic Metal–Organic Framework as Highly Electrochemiluminescence Sensing Platform for Thrombin

• Published in: Analytical chemistry (Washington) Vol. 94; no. 14; pp. 5707 - 5714
• Main Authors: Li, Peipei, Luo, Luo, Cheng, Dan, Sun, Yan, Zhang, Youyu, Liu, Meiling, Yao, Shouzhuo
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 12.04.2022
• Subjects: Analytical chemistry; Aptamers; Biomarkers; Biosensing Techniques; Chemistry; coordination polymers; detection limit; Diagnosis; early diagnosis; Electrochemical Techniques; Electrochemiluminescence; Hydrothermal reactions; Immobilization; Immunoassay; Immunoassays; Limit of Detection; Luminescent Measurements; Metal Nanoparticles; Metal-organic frameworks; Metal-Organic Frameworks - chemistry; micropores; oligonucleotides; Porphyrins; Reaction time; structure-activity relationships; Surface area; Surface charge; Thrombin; Tuning; Zirconium; Zirconium - chemistry

An electrochemiluminescence (ECL) sensor provides a sensitive and convenient method for early diagnosis of diseases; however, it is still a challenge to develop simple and sensitive sensing platforms based on efficient ECL signals and luminophore groups. Porphyrin-based metal–organic frameworks (MOF...