Active Modulation of States of Prestress in Self-Assembled Short Peptide Gels

• Published in: Biomacromolecules Vol. 20; no. 4; pp. 1719 - 1730
• Main Authors: Cox, Henry, Cao, Meiwen, Xu, Hai, Waigh, Thomas A, Lu, Jian R
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 08.04.2019
• Subjects: artificial intelligence; crosslinking; fluorescence microscopy; Hot Temperature; hydrogels; Hydrogels - chemistry; modulus of elasticity; osmotic pressure; Peptides - chemistry; Shear Strength; solutes; synthetic peptides; temperature; therapeutics; viscoelasticity; wavelengths

Peptide hydrogels are excellent candidates for medical therapeutics due to their tuneable viscoelastic properties, however, in vivo they will be subject to various osmotic pressures, temperature changes, and biological co-solutes, which could alter their performance. Peptide hydrogels formed from th...