Flexing the Electrified Meniscus:  The Birth of a Jet in Electrosprays

• Published in: Analytical chemistry (Washington) Vol. 76; no. 14; pp. 4202 - 4207
• Main Authors: Marginean, Ioan, Parvin, Lida, Heffernan, Linda, Vertes, Akos
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 15.07.2004
• Subjects: Analytical chemistry; Chemistry; Comparative analysis; Exact sciences and technology; Ions; Ions - chemistry; Proteins - analysis; Proteins - chemistry; Scientific apparatus & instruments; Spectrometric and optical methods; Spectrometry, Mass, Electrospray Ionization - instrumentation; Spectrum analysis; Fourier transform spectroscopy; Imaging; Oscillation frequency; Spraying; Pulse; Mass spectrometry; Electrospray; Monitoring; Protein

Spraying of liquids through an electrified meniscus has become a method of choice to produce ions from large biomolecules. Using mass spectrometry, the generated ions can be analyzed to provide detailed information on their composition and structure. This technique enables high-throughput protein an...