In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

• Published in: Antimicrobial Agents and Chemotherapy Vol. 58; no. 3; pp. 1652 - 1663
• Main Authors: LAI, Ming-Tain, MEIZHEN FENG, CAUCHON, Elizabeth, CAMPEAU, Louis-Charles, GROBLER, Jay, YOUWEI YAN, DUCHARME, Yves, COTE, Bernard, ASANTE-APPIAH, Ernest, HAZUDA, Daria J, MILLER, Michael D, FALGUEYRET, Jean-Pierre, TAWA, Paul, WITMER, Marc, DISTEFANO, Daniel, YUAN LI, BURCH, Jason, SACHS, Nancy, MEIQING LU
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.2014
• Subjects: Anti-HIV Agents; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - adverse effects; Anti-HIV Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Drug Synergism; HIV Infections - drug therapy; HIV Reverse Transcriptase; HIV Reverse Transcriptase - antagonists & inhibitors; HIV Reverse Transcriptase - metabolism; HIV-1; HIV-1 - drug effects; HIV-1 - enzymology; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; In Vitro Techniques; Infectious diseases; Macrophages - drug effects; Medical sciences; Monocytes - drug effects; Pharmacology. Drug treatments; Pyridones; Pyridones - adverse effects; Pyridones - pharmacology; Triazoles; Triazoles - adverse effects; Triazoles - pharmacology; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virus Replication - drug effects; Immunopathology; HIV-1 virus; Non nucleoside compound; Retroviridae; AIDS; Immune deficiency; Lentivirus; In vitro; Infection; Virus; Characterization; Viral disease; Reverse transcriptase inhibitor; Antiviral; Human immunodeficiency virus
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.02403-13

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