Effects of Essential Oils from Herbal Plants and Citrus Fruits on DNA Polymerase Inhibitory, Cancer Cell Growth Inhibitory, Antiallergic, and Antioxidant Activities

• Published in: Journal of agricultural and food chemistry Vol. 60; no. 45; pp. 11343 - 11350
• Main Authors: Mitoshi, Mai, Kuriyama, Isoko, Nakayama, Hiroto, Miyazato, Hironari, Sugimoto, Keiichiro, Kobayashi, Yuko, Jippo, Tomoko, Kanazawa, Kazuki, Yoshida, Hiromi, Mizushina, Yoshiyuki
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 14.11.2012
• Subjects: absorbance; Animals; Anti-Allergic Agents; Anti-Allergic Agents - pharmacology; antioxidant activity; Antioxidants; Antioxidants - pharmacology; Aroma and flavouring agent industries; Biological and medical sciences; calcium; cell growth; Cell Line, Tumor; Cell Proliferation; Cell Proliferation - drug effects; chamomile; chemistry; Citrus; Citrus - chemistry; citrus fruits; colorectal neoplasms; DNA; DNA repair; DNA-directed DNA polymerase; drug effects; drug therapy; Enzyme Inhibitors; Enzyme Inhibitors - pharmacology; essential oils; Female; Food industries; Fruit and vegetable industries; Fundamental and applied biological sciences. Psychology; Humans; Hypersensitivity; Hypersensitivity - drug therapy; Hypersensitivity - immunology; immunology; leukemia; Matricaria chamomilla; Mice; Mice, Inbred ICR; Nucleic Acid Synthesis Inhibitors; Oils, Volatile; Oils, Volatile - pharmacology; pharmacology; Plant Extracts; Plant Extracts - pharmacology; Plant Oils; Plant Oils - pharmacology; Plants, Medicinal; Plants, Medicinal - chemistry; Rats; cancer cell growth inhibitory activity; DNA polymerase inhibitory activity; anti-β-hexosaminidase release activity; essential oil; antiallergic activity; antioxidant activity; chamomile; α-bisabolol oxide A; anti-inflammatory activity; Fruit; Growth; Essential oil plant; Citrus fruit; Antiinflammatory agent; Oxides; Malignant tumor; Antioxidant; DNA; Essential oil; Chamomile; Cell; Release; Cancer

In this study, the biological activity of 20 essential oils (EOs) from herbal plants and citrus fruits were investigated in terms of mammalian DNA polymerase (pol) inhibitory activity, cancer cell (human colon carcinoma, HCT116) growth inhibitory activity, antiallergic activity, as anti-β-hexosamini...