Interaction of 3β-Amino-5-cholestene with Phospholipids in Binary and Ternary Bilayer Membranes

• Published in: Langmuir Vol. 28; no. 1; pp. 648 - 655
• Main Authors: Lönnfors, Max, Engberg, Oskar, Peterson, Blake R, Slotte, J. Peter
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 10.01.2012
• Subjects: Biological Interfaces: Biocolloids, Biomolecular and Biomimetic Materials; Calorimetry, Differential Scanning; Chemistry; Cholestenes - chemistry; cholesterol; Colloidal state and disperse state; enthalpy; Exact sciences and technology; General and physical chemistry; Lipid Bilayers; Membranes; phase transition; phospholipids; Phospholipids - chemistry; sphingomyelins; thermal stability; Crystalline phase; Mixed bilayer; Enthalpy; Fluid; Phospholipid; Replacement; Liquid phase; Bilayer; Phase transitions; Cholesterol; Lifetime; Acids; Anisotropy; Ordering; Membrane; Models; Thermodynamic properties

3β-Amino-5-cholestene (aminocholesterol) is a synthetic sterol whose properties in bilayer membranes have been examined. In fluid palmitoyl sphingomyelin (PSM) bilayers, aminocholesterol and cholesterol were equally effective in increasing acyl chain order, based on changes in diphenylhexatriene (DP...