Preventive Effects of Taurine on Development of Hepatic Steatosis Induced by a High-Fat/Cholesterol Dietary Habit

• Published in: Journal of agricultural and food chemistry Vol. 59; no. 1; pp. 450 - 457
• Main Authors: Chang, Yuan-Yen, Chou, Chung-Hsi, Chiu, Chih-Hsien, Yang, Kuo-Tai, Lin, Yi-Ling, Weng, Wei-Lien, Chen, Yi-Chen
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 12.01.2011
• Subjects: animal models; Animals; antioxidant activity; Biological and medical sciences; cholesterol; Cholesterol, Dietary - adverse effects; Cholesterol, Dietary - metabolism; Cricetinae; diet-related diseases; dietary fat; Dietary Fats - adverse effects; Dietary Fats - metabolism; Disease Models, Animal; disease prevention; fat intake; fatty liver; Fatty Liver - drug therapy; Fatty Liver - genetics; Fatty Liver - metabolism; Fatty Liver - prevention & control; Food industries; Fundamental and applied biological sciences. Psychology; Gene Expression - drug effects; hamsters; hepatoprotective effect; high fat diet; Humans; Ion Channels - genetics; Ion Channels - metabolism; lipid metabolism; Male; Mesocricetus; Mitochondrial Proteins - genetics; Mitochondrial Proteins - metabolism; Molecular Nutrition; Non-alcoholic Fatty Liver Disease; PPAR alpha - genetics; PPAR alpha - metabolism; taurine; Taurine - administration & dosage; Uncoupling Protein 2; lipid homeostasis; taurine; hepatic/fecal lipids; Antioxidant capacity/enzyme; serum lipids; hepatic steatosis; Taurine; Enzyme; Lipids; Antioxidant; Cholesterol; Development; Fat; Serum; Feces

Nonalcoholic fatty liver (NAFL) is also called hepatic steatosis and has become an emergent liver disease in developed and developing nations. This study was to exam the preventive effects of taurine (Tau) on the development of hepatic steatosis via a hamster model. Although hepatic steatosis of ham...