Design, Synthesis and Insecticidal Activity of Novel Phenylpyrazoles Containing a 2,2,2-Trichloro-1-alkoxyethyl Moiety

• Published in: Journal of agricultural and food chemistry Vol. 58; no. 8; pp. 4992 - 4998
• Main Authors: Zhao, Qiqi, Li, Yongqiang, Xiong, Lixia, Wang, Qingmin
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 28.04.2010; Amer Chemical Soc
• Subjects: 2,2,2-trichloro-1-alkoxyethyl moiety; Agriculture; Agriculture, Multidisciplinary; Animals; Biological and medical sciences; chemical analysis; chemical composition; chemical synthesis; Chemistry; Chemistry, Applied; Crop and Animal Protection Chemistry; design; enantiomers; Food industries; Food Science & Technology; Fundamental and applied biological sciences. Psychology; insect pests; insecticidal properties; Insecticides; Insecticides - chemical synthesis; Insecticides - chemistry; Insecticides - pharmacology; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Moths; pest control; pharmacology; phenylpyrazoles; Physical Sciences; Plutella xylostella; Pyrazoles; Pyrazoles - chemical synthesis; Pyrazoles - chemistry; Pyrazoles - pharmacology; Science & Technology; Stereoisomerism; synthesis; toxicity; GABA receptor; Phenylpyrazole; 2,2,2-trichloro-1-alkoxyethyl; insecticidal activity; broad spectrum; RESISTANCE; DERIVATIVES; Design; Insecticide; Synthesis; Pesticides; Neurotransmitter; GABA; Spectrum

A series of novel phenylpyrazoles containing a 2,2,2-trichloro-1-alkoxyethyl moiety were designed and synthesized via the key intermediate 5-trichloroethylideneimino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-alkylsulfenylpyrazole (5). The addition reaction of the imine 5 was closely related...