Competitive Inhibition of Renal Tubular Secretion of Gemifloxacin by Probenecid - Landersdorfer, Cornelia B.; Kirkpatrick, Carl M. J.; Kinzig, Martina; Bulitta, Jürgen B.; Holzgrabe, Ulrike; Drusano, George L.; Sörgel, Fritz (Antimicrobial Agents and Chemotherapy, 2009)
Keywords: Adjuvants, Pharmaceutic; Adjuvants, Pharmaceutic - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Female; Fluoroquinolones; Fluoroquinolones - blood; Fluoroquinolones - pharmacokinetics; Fluoroquinolones - urine; Humans; Kidney Function Tests; Kidney Tubules; Kidney Tubules - drug effects; Kidney Tubules - metabolism; Male; Medical sciences; Metabolic Clearance Rate - drug effects; Naphthyridines; Naphthyridines - blood; Naphthyridines - pharmacokinetics; Naphthyridines - urine; Pharmacology; Pharmacology. Drug treatments; Probenecid; Probenecid - blood; Probenecid - pharmacology; Probenecid - urine; Gemifloxacin; Fluoroquinolone derivatives; Renal tubule; Sulfonamides; Secretion; Antibacterial agent; Competitive inhibition; Uricosuric agent; Quinolone derivatives; Probenecid