Development and Validation of a Penicillin Allergy Clinical Decision Rule

• Published in: JAMA internal medicine Vol. 180; no. 5; p. 745
• Main Authors: Trubiano, Jason A, Vogrin, Sara, Chua, Kyra Y L, Bourke, Jack, Yun, James, Douglas, Abby, Stone, Cosby A, Yu, Roger, Groenendijk, Lauren, Holmes, Natasha E, Phillips, Elizabeth J
• Format: Journal Article
• Language: English
• Published: United States 01.05.2020
• Subjects: Aged; Anti-Bacterial Agents - adverse effects; Clinical Decision Rules; Drug Hypersensitivity - etiology; Female; Humans; Male; Middle Aged; Penicillins - adverse effects; Prospective Studies; Risk Assessment

Penicillin allergy is a significant public health issue for patients, antimicrobial stewardship programs, and health services. Validated clinical decision rules are urgently needed to identify low-risk penicillin allergies that potentially do not require penicillin skin testing by a specialist. To d...