Isolation, Structural Elucidation, and Liquid Chromatography–Mass Spectrometry Analysis of Steroidal Glycosides from Polygonatum odoratum

• Published in: Journal of Agricultural and Food Chemistry Vol. 66; no. 2; pp. 521 - 531
• Main Authors: Liu, Qingbo, Li, Wei, Nagata, Kazuya, Fu, Hongwei, Okada, Shunpei, Tanabe, Ikumi, Kobori, Yumi, Higai, Koji, Norie, Wada, Sasaki, Tatsunori, Asada, Yoshihisa, Zhao, Huanxin, Bai, Hong, Koike, Kazuo
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 17.01.2018; American Chemical Society (ACS); Amer Chemical Soc
• Subjects: Agriculture; Agriculture, Multidisciplinary; autumn; biosynthesis; Cell Proliferation; Cell Survival; chemical constituents of plants; chemical reactions; Chemistry; Chemistry, Applied; chemotaxonomy; Chromatography, Liquid; Food Science & Technology; functional foods; Geographical Locations; Glycosides; Hep G2 Cells; hepatoma; human cell lines; Humans; inhibitory concentration 50; Life Sciences & Biomedicine; liquid chromatography; Mass Spectrometry; Molecular Structure; neoplasm cells; Oriental traditional medicine; Physical Sciences; Plant Extracts; Polygonatum; Polygonatum odoratum; quality control; Rhizome; rhizomes; Science & Technology; spectral analysis; spring; Steroids; structural elucidation; antiproliferation activity; Polygonatum odoratum; LC−MS analysis; steroidal glycosides; APOPTOSIS; LC-MS analysis; SAPONINS; antiptoliferation activity; RHIZOMES

The rhizomes of Polygonatum odoratum represent a traditional Chinese medicine and functional food. A phytochemical investigation resulted in the isolation of eight steroidal glycosides (1–8), including two new compounds, polygonatumosides F (1) and G (2). The structures were elucidated by spectrosco...