Identification and Evaluation of a Highly Effective Fusion Inhibitor for Human Metapneumovirus

• Published in: Antimicrobial Agents and Chemotherapy Vol. 52; no. 1; pp. 279 - 287
• Main Authors: Deffrasnes, Céline, Hamelin, Marie-Ève, Prince, Gregory A., Boivin, Guy
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.01.2008; American Society for Microbiology (ASM)
• Subjects: Amino Acid Sequence; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - chemistry; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Biological and medical sciences; Cell Line; Cell Line, Tumor; Escherichia coli; Female; Human immunodeficiency virus; Human metapneumovirus; Human respiratory syncytial virus; Humans; Inhibitory Concentration 50; Medical sciences; Membrane Fusion; Membrane Fusion - drug effects; Metapneumovirus; Metapneumovirus - drug effects; Metapneumovirus - pathogenicity; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Parainfluenza virus; Paramyxoviridae Infections; Paramyxoviridae Infections - drug therapy; Paramyxoviridae Infections - virology; Peptides; Peptides - chemistry; Peptides - pharmacology; Peptides - therapeutic use; Pharmacology. Drug treatments; Viral Fusion Proteins; Viral Fusion Proteins - chemistry; Human Metapneumovirus; Evaluation; Identification; Efficiency; Fusion inhibitor

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