Unique Evolution of Antiviral Tetherin in Bats

• Published in: Journal of virology Vol. 96; no. 20; p. e0115222
• Main Authors: Hayward, Joshua A., Tachedjian, Mary, Johnson, Adam, Irving, Aaron T., Gordon, Tamsin B., Cui, Jie, Nicolas, Alexis, Smith, Ina, Boyd, Victoria, Marsh, Glenn A., Baker, Michelle L., Wang, Lin-Fa, Tachedjian, Gilda
• Format: Journal Article
• Language: English
• Published: 1752 N St., N.W., Washington, DC American Society for Microbiology 26.10.2022
• Subjects: Genetic Diversity and Evolution; Virology; bats; BST-2; viruses; innate immunity; antiviral; restriction factors; evolution; filoviruses; tetherin; retroviruses

Bats are recognized as important reservoirs of viruses deadly to other mammals, including humans. These infections are typically nonpathogenic in bats, raising questions about host response differences that might exist between bats and other mammals. Tetherin is a restriction factor which inhibits t...