Unprecedented Cyclization Catalyzed by a Cytochrome P450 in Benzastatin Biosynthesis - Tsutsumi, Hayama; Katsuyama, Yohei; Izumikawa, Miho; Takagi, Motoki; Fujie, Manabu; Satoh, Noriyuki; Shin-ya, Kazuo; Ohnishi, Yasuo (Journal of the American Chemical Society, 2018)
Keywords: acetic acid; biochemical pathways; biosynthesis; catalytic activity; Chemistry; Chemistry, Multidisciplinary; chlorides; cytochrome P-450; ethyleneimine; functional diversity; gene targeting; genetically modified organisms; iron; Lewis bases; moieties; multigene family; Physical Sciences; Science & Technology; Streptomyces; transferases; N-OXYGENASE AURF; STREPTOMYCES-COELICOLOR A3; CRYSTAL-STRUCTURE; NATURAL-PRODUCTS; ENZYMES; P450; NITROSPOREUS; FREE-RADICAL SCAVENGERS; FLAVIOLIN SUBSTRATE MOLECULES; CELL PROTECTING ACTIVITY