Fluorescence Spectroscopic Analysis of Lateral and Transbilayer Fluidity of Exosome Membranes

• Published in: Langmuir Vol. 38; no. 48; pp. 14695 - 14703
• Main Authors: Yasuda, Tomokazu, Watanabe, Hirofumi, Hirosawa, Koichiro M., Suzuki, Kenichi G. N., Suga, Keishi, Hanashima, Shinya
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 06.12.2022
• Subjects: Cell Membrane - metabolism; Exosomes - metabolism; Lipid Bilayers - chemistry; Membrane Fluidity; Spectrometry, Fluorescence

Exosomes are small extracellular vesicles (sEVs) involved in distal cell–cell communication and cancer migration by transferring functional cargo molecules. Membrane domains similar to lipid rafts are assumed to occur in exosome membranes and are involved in interactions with target cells. However,...