Synthesis of Cyclobutane-Fused Angular Tetracyclic Spiroindolines via Visible-Light-Promoted Intramolecular Dearomatization of Indole Derivatives

• Published in: Journal of the American Chemical Society Vol. 141; no. 6; pp. 2636 - 2644
• Main Authors: Zhu, Min, Zheng, Chao, Zhang, Xiao, You, Shu-Li
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 13.02.2019; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Multidisciplinary; cycloaddition reactions; diastereoselectivity; energy transfer; moieties; Physical Sciences; Science & Technology; N-BENZOYLINDOLE; CATALYSIS; ALKYLATION; PRENYLATION; CONSTRUCTION; PHOTOCATALYSIS; 2+2 PHOTOCYCLOADDITION REACTIONS; CYCLIZATION; PYRROLOINDOLINES; PHOTOCHEMICAL CYCLOADDITION REACTIONS

An intramolecular dearomatization of indole derivatives based on visible-light-promoted [2+2] cycloaddition was achieved via energy transfer mechanism. The highly strained cyclobutane-fused angular tetracyclic spiroindolines, which were typically unattainable under thermal conditions, could be direc...