Irradiation-Induced Heck Reaction of Unactivated Alkyl Halides at Room Temperature

• Published in: Journal of the American Chemical Society Vol. 139; no. 50; pp. 18307 - 18312
• Main Authors: Wang, Guang-Zu, Shang, Rui, Cheng, Wan-Min, Fu, Yao
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 20.12.2017; Amer Chemical Soc
• Subjects: ambient temperature; catalytic activity; Chemistry; Chemistry, Multidisciplinary; cross-coupling reactions; irradiation; Lewis acids; ligands; light emitting diodes; organobromine compounds; palladium; phosphine; Physical Sciences; Science & Technology; CATALYSIS; CROSS-COUPLING REACTIONS; PD; COMPLEXES; ARYL; SUBSTITUTION-REACTIONS; BROMIDES

The palladium-catalyzed Mizoroki–Heck reaction is arguably one of the most significant carbon–carbon bond-construction reactions to be discovered in the last 50 years, with a tremendous number of applications in the production of chemicals. This Nobel-Prize-winning transformation has yet to overcome...